Neuropathic Pain

Common Cold

Paroxysmal cold hemoglobinuria

Cold agglutinin disease

Pain

Pain is defined by the International Association for the Study of Pain as “an unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in term...

What Other Neuropathic Pain Drugs Are Missing

By Cris Frangold: When doctors diagnose patients with neuropathic pain, it almost always comes as a shock to patients and family members because it is often difficult to pinpoint and even more difficu...

Peripheral neuropathic pain patch treatments: an interview with Anne Hodgkins, Astellas Pharma

Peripheral neuropathic pain is caused by lesion or disease to the peripheral somatosensory nervous system. Nerve damage that can lead to peripheral neuropathic pain can happen as a result of a range o...

Blocking Neuropathic Pain Before It Starts

Using tiny spheres filled with an anesthetic derived from a shellfish toxin, researchers at Boston Children's Hospital and the Massachusetts Institute of Technology have developed a way to delay the r...

Putting a block on neuropathic pain before it starts: Tiny spheres filled with anesthetic from a shellfish toxin

Using tiny spheres filled with anesthetic from a shellfish toxin, researchers have developed a way to delay the rise of neuropathic pain, chronic pain from flawed signals transmitted by damaged nerves...

Pain: Transplanted precursors halt neuropathic pain

Transplanted forebrain interneuron precursors integrate into spinal cord circuits and relieve neuropathic pain symptoms.

Exercise-Related Reductions In Neuropathic Pain And Inflammatory Mediators

Exercise helps to alleviate pain related to nerve damage (neuropathic pain) by reducing levels of certain inflammation-promoting factors, suggests an experimental study in the June issue of Anesthesia...

Pfizer receives FDA approval for Lyrica to manage neuropathic pain associated with SCI

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) approved the use of Lyrica (pregabalin) capsules CV for the management of neuropathic pain associated with spinal cord inju...

Gene therapy at center of UTMB effort to eliminate neuropathic pain

University of Texas Medical Branch at Galveston researchers have been awarded a five-year, $1.8 million grant by the National Institute of Neurological Disorders and Stroke to apply the techniques of...

Translational investigation and treatment of neuropathic pain.

ABSTRACT: Neuropathic pain develops from a lesion or disease affecting the somatosensory system. Translational investigations of neuropathic pain by using different animal models reveal that periphera...

Ethosuximide reduces allodynia and hyperalgesia and potentiates morphine effects in the chronic constriction injury model of neuropathic pain.

Neuropathic pain is caused by a lesion or disease of the somatosensory nervous system and treatment of neuropathic pain remains a challenge. The purpose of the present study was to examine the effect...

Increased miR-195 aggravates neuropathic pain by inhibiting autophagy following peripheral nerve injury.

Following peripheral nerve injury (PNI) microglia proliferates and adopts inflammation that contributes to development and maintenance of neuropathic pain. miRNAs and autophagy are two important facto...

Pain in Patients with Chronic Idiopathic Axonal Polyneuropathy.

Background/Aims: Pain in patients with chronic idiopathic axonal polyneuropathy (CIAP) has never been studied in detail. The aim of the study was to investigate the pain experienced by patients with C...

Exploring the potential of telmisartan in chronic constriction injury-induced neuropathic pain in rats.

The present study was designed to investigate the potential of telmisartan, an angiotensin AT(1) receptor, in chronic constriction injury-induced neuropathic pain in rats. Four loose ligatures were pl...