Search Results for "Colorectal Cancer Neoadjuvant"
Original Source: Influence of Neoadjuvant Therapy on the Resectability of Hepatic Metastases From Colorectal Cancers
More and more colorectal surgeons believe that surgical resections of hepatic metastases from colorectal cancer is the only chance for cure of patients. The five-year survival for patients with hepatic metastasis from colorectal cancer after surgical resection is approximately 30 %. However, most hepatic metastases from colorectal cancer were inoperable. With the progress of chemotherapy, for example, the combination of the 5-Fu, leucovorin, and oxaliplatin, some surgeons advoc...
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Neoadjuvant therapy is the administration of therapeutic agents before the main treatment. One example is neoadjuvant hormone therapy prior to radical radiotherapy for adenocarcinoma of the prostate...
Colon or Colorectal cancer is the growth of malignant polyps on the colon, bowel, anus and rectum. Growths in these locations can be benign, and removed by colonoscopy, but they have a risk of becom...
APC stands for adenomatous polyposis coli, a form of colorectal cancer and is a tumour suppressor
APC stands for adenomatous polyposis coli, a form of colorectal cancer and is a tumour suppressor. When APC it mutated, it can cause this particular type of colorectal cancer. When not present in it...
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Progression in colorectal carcinomatosis may not rule out cure
NEW YORK (Reuters Health) - Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis (PC) from colorectal cancer can be undertaken with a curative...
Rectal CA recurs similarly after short- or long-course neoadjuvant radiation
NEW YORK (Reuters Health) - In a recent study of patients with stage T3 rectal cancer, neoadjuvant short-course radiation plus postop chemotherapy didn't prevent recurrence any better than a longe...
Neoadjuvant Chemotherapy More Suitable For Breast Cancer Patients Who Lack RB Gene
Breast cancer patients whose tumors lacked the retinoblastoma tumor suppressor gene (RB) had an improved pathological response to neoadjuvant chemotherapy, researchers at Thomas Jefferson University H...
Sentinel-lymph-node biopsy is a reliable diagnostic method before neoadjuvant chemotherapy. After systemic treatment or early sentinel-lymph-node biopsy, the procedure has a lower detection rate and a...
PET and CT can't show response to neoadjuvant therapy of rectal CA
NEW YORK (Reuters Health) - After neoadjuvant chemoradiation for locally advanced rectal cancer, PET and CT scans aren't accurate enough to detect a pathological complete response, according to a...
Zaltrap Approved for Metastatic Colorectal Cancer
The U.S. Food and Drug Administration (FDA) has approved Zaltrap® (ziv-aflibercept) for use in combination with the FOLFIRI chemotherapy regimen (folinic acid, fluorouracil, and ironotecan) to treat...
Breast cancer patients who lack RB gene respond better to neoadjuvant chemotherapy
(Thomas Jefferson University) Breast cancer patients whose tumors lacked the retinoblastoma tumor suppressor gene (RB) had an improved pathological response to neoadjuvant chemotherapy, researchers at...
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PURPOSE: The aim of this study was to determine the effect of a longer interval between neoadjuvant chemoradiation and surgery on perioperative morbidity and oncologic outcomes. METHODS: A colorectal...
Optimizing resection for "responding" hepatic metastases after neoadjuvant chemotherapy.
Fifty percent of patients with colorectal cancer will develop metastases at some time during their disease, with the liver being the most common site. Recent advances in the treatment of metastatic co...
BACKGROUND: Several clinical risk scores (CRSs) for the outcome of patients with colorectal liver metastases have been validated, but not in patients undergoing neoadjuvant chemotherapy. Therefore, th...
To ascertain the approach and degree of consensus of pathologists in the handling and regression grading of colorectal cancer resection specimens treated with neoadjuvant chemoradiation, a ten-part qu...
BACKGROUND: Despite development in therapeutic strategies, such as neoadjuvant concurrent chemoradiotherapy (CCRT), the prognosis of colorectal cancer remains relatively poor. Cancer stem cells (CSC)...
