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Search Results for "Computer Model Predicts Side Effects"

20:47 EDT 19th June 2013 | BioPortfolio

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RPL554

Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...

Kadcyla (ado-trastuzumab emtansine)

Kadcyla™ (ado-trastuzumab emtansine or T-DM1) for the treatment of people with HER2-positive metastatic breast cancer (mBC) who have received prior treatment with Herceptin® (trastuzumab)...

Gastrointestinal Effects

Immunocytokines

Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targ...

Management of Adverse Effects

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Computer Method Predicts Drug Side Effects

Researchers have used computer modeling to predict the side effects of hundreds of medications. The technique could aid in the future development and use of drugs.

Computer system predicts NCAA basketball champion

When Georgia Tech opens the doors to the Georgia Dome next month as the host institution for the 2013 Final Four, expect third-seeded Florida to walk out as the national champion. That's the predictio...

Computer model predicts when viruses become infectious

A new computer model could help scientists predict when a particular strain of avian influenza might become infectious from bird to human, according to a report to be published in the International Jo...

Will ‘Side Effects’ Have Side Effects For Pharma?

There have been several movies over the years that have, in various ways, focused on the pharmaceutical industry and the latest to do so is ‘Side Effects,’ the Steve Soderbergh film that d...

Statin Side Effects Are Usually Overcome

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

Statin Therapy Side Effects Go Away With Persistence

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

SNPing side effects: Sidebar: Inform Genomics Inc. Corporate Profile

SNPing side effects Inform Genomics Inc. Boston, Mass. Technology: SNP-based test to predict chemotherapy side effects Disease focus: Diagnostic Clinical status: NA Founded: 2010 by Ed Rubenstein, Sus...

New statistical model predicts global decline in working-age adults to support elderly people

A new statistical model predicts that by 2100 the number of people older than 85 worldwide will increase more than previously estimated, and there will be fewer working-age adults to support them than...

Matching PubMed Articles

A general model for effects of temperature on ectotherm ontogenetic growth and development.

The temperature size rule (TSR) is the tendency for ectotherms to develop faster but mature at smaller body sizes at higher temperatures. It can be explained by a simple model in which the rate of gro...

Patients' attitudes toward side effects of antidepressants: an Internet survey.

Patients' attitudes toward side effects of antidepressants are likely to differ according to gender, which has not yet been fully addressed in the literature. From the 228,310 registrants, 1,305 parti...

On the Consistency Rule in Causal Inference: Axiom, Definition, Assumption, or Theorem?

In 2 recent communications, Cole and Frangakis (Epidemiology. 2009;20:3-5) and VanderWeele (Epidemiology. 2009;20:880-883) conclude that the consistency rule used in causal inference is an assumption...

Structural and hydrodynamic simulation of an acute stenosis-dependent thrombosis model in mice.

Platelet activation under blood flow is thought to be critically dependent on the autologous secretion of soluble platelet agonists (chemical activators) such as ADP and thromboxane. However, recent e...

Butler-Volmer-Monod model for describing bio-anode polarization curves.

A kinetic model of the bio-anode was developed based on a simple representation of the underlying biochemical conversions as described by enzyme kinetics, and electron transfer reactions as described...

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