Search Results for "Copd Sputum Neutrophilia"
Original Source: Two-Part Study to Evaluate the Dose Response of SCH 527123 on Sputum Neutrophilia Following Ozone Challenge in Healthy Subjects and Chronic Obstructive Pulmonary Disease (COPD) Patients (P05567 AM7)
Trial to evaluate the dose response of SCH 527123 in reducing inflammation from an ozone-induced sputum neutrophilia in both healthy subjects and subjects with COPD.
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COPD (chronic obstructive pulmonary disease) is used for a number of conditions including chronic bronchitis and emphysema, which all lead to the airways in the lungs becoming damaged and thus...
Treatment of Acute COPD Exacerbation
Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...
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Preventive Antibiotic May Benefit COPD Sufferers
Patients suffering from the chronic lung condition COPD, which is the third-leading cause of death and disability in the United States, may benefit greatly from a three-times-a-week dose of an antibio...
Chronic Obstructive Pulmonary Disease
Chronic obstructive pulmonary disease (COPD) is one of the most common lung disorders in adults and includes chronic bronchitis and emphysema. In COPD, the airway passages (known as bronchi and bronch...
COPD Foundation and WebMD to Promote COPD Risk Awareness
The COPD Foundation (COPDF) announced today the launch of a COPD Risk Screener on WebMD. The COPD Risk Screener asks consumers a series of questions related to breat...
Sputum color guides antibiotic treatment in COPD
Withholding antibiotic treatment from hospitalized chronic obstructive lung disease patients with nonpurulent sputum does not negatively affect outcomes, a pilot study shows.
Microbial composition of induced sputum altered in mild asthma
The microbial composition of sputum in patients with mild asthma differs from that in individuals without the condition, results from a US study show.
COPD Diagnoses May Increase With 5-Question Survey
A simple, five-question patient-administered survey (COPD-PS) may lead to increased diagnoses of chronic obstructive pulmonary disease (COPD). Researchers from David Geffen School of Medicine at UCLA,...
The COPD Partnering 2007-2012 provides understanding and access to the COPD partnering deals and agreements entered into by the worlds leading healthcare companies. The report provides an analysis o...
COPD patients are more oliley to suffre from depression
Patients suffering from chronic obstructive pulmonary disease (COPD) typically suffer from depression more frequently than those without COPD, resulting in higher levels of disability and illness and...
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OBJECTIVE: To investigate the possible role of anaphylatoxin(C3a) in chronic obstructive pulmonary disease (COPD). METHODS: Sixty-four elderly patients with COPD (including 51 males, 13 females, 31 wi...
Airway inflammation and mannitol challenge test in COPD.
ABSTRACT: BACKGROUND: Eosinophilic airway inflammation has successfully been used to tailor anti-inflammatory therapy in chronic obstructive pulmonary disease (COPD). Airway hyperresponsiveness (AHR)...
Inflammatory Biomarkers in Sputum Predict COPD Exacerbations.
INTRODUCTION: Exacerbations in chronic obstructive pulmonary disease (COPD) reduce quality of life and are associated with a more rapid deterioration of the disease. It is desirable to predict an onco...
Non-Invasive Biomarkers in Exacerbations of Obstructive Lung Disease.
BACKGROUND AND OBJECTIVE: Current methods of diagnosing exacerbations of asthma and COPD shed little light on their aetiology or pathophysiology. Non-invasive diagnostic methods could be helpful in th...
ABSTRACT: BACKGROUND: Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and COPD. MMP-12 (macrophage elastas...
