Search Results for "Curcumin Absorption"
Original Source: Investigation of the absorption mechanism of solubilized curcumin using caco-2 cell monolayers.
Curcumin is a bioactive compound with poor oral bioavailability. Low water solubility and rapid metabolism are two known limiting factors, but the absorption mechanism of solubilized curcumin remains unclear. This study investigated the permeation mechanism of solubilized curcumin using an in vitro Caco-2 cell monolayer model. It was shown that curcumin permeated across the monolayers fairly rapidly [P(app)(A-B) = (7.1 ± 0.7) × 10(-6) cm/s] and the permeation mechanism was found as passive diffusion [P(ap...
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Disorders of Calcium Concentration
Calcium (Ca) is required for the proper functioning of muscle contraction, nerve conduction, hormone release, and blood coagulation. In addition, proper Ca concentration is required for various othe...
Vitamin C (ascorbic acid) plays a role in collagen, carnitine, hormone, and amino acid formation. It is essential for wound healing and facilitates recovery from burns. Vitamin C is also an antioxid...
Vitamin D is a fat-soluble vitamin that is produced endogenously when ultraviolet rays from sunlight strike the skin, and can be found in some foods. Vitamin D promotes calcium absorption in the g...
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Type: Original PaperVaginal administration is a promising alternative to the per-oral route in achieving systemic or local therapeutic effects, when intestinal drug absorption is hindered by problemat...
Curcumin Also Inhibits Metastasis from Prostate Cancer
Researchers have now shown that curcumin, the key medicinal ingredient of turmeric, can also inhibit formation of metastases from...
Powdered turmeric has been used for centuries to treat osteoarthritis and other illnesses. Its active ingredient, curcumin, inhibits inflammatory reactions. [...]
Type: Original PaperThe therapeutic effects of curcumin in treating Alzheimer’s disease (AD) depend on the ability to penetrate the blood–brain barrier. The latest nanoparticle technology can help...
Curcumin Inhibits Prostate Cancer Metastases
Curcumin, an ingredient of the Indian spice Turmeric, has been shown to stop the formation of metastases in prostate cancer patients, researchers from Ludwig-Maximilians-Universität (LMU) in Munich...
Prostate cancer: Curcumin curbs metastases
Powdered turmeric has been used for centuries to treat osteoarthritis and other illnesses. Its active ingredient, curcumin, inhibits inflammatory reactions. A new study led by a research team at Ludwi...
Quick Study: Curry Favors Type 2 Diabetes Prevention
The study: Curcumin extract, found in the spice turmeric, may help prevent Type 2 diabetes. In a double-blind placebo study, 240 people with pre-diabetes (a precursor to full-blown diabetes) were rand...
Prostate cancer: Curcumin curbs metastases, study shows
Powdered turmeric has been used for centuries to treat osteoarthritis and other illnesses. Its active ingredient, curcumin, inhibits inflammatory reactions. A new study now shows that it can also inhi...
Matching PubMed Articles
Spectrometric study on the interaction of dodecyltrimethylammonium bromide with curcumin.
The interaction between dodecyltrimethylammonium bromide (DTAB) and curcumin has been studied in pH 5.0 sodium phosphate buffer using absorption and fluorescence measurements. With increasing DTAB con...
PURPOSE: Curcumin has shown a variety of biological activity for various human diseases including cancer in preclinical setting. Its poor oral bioavailability poses significant p...
The spectroscopic properties of liposomal curcumin in pH 7.0 sodium phosphate buffer were studied at various curcumin concentrations and temperatures. At 25 °C, liposomal curcumin exhibited much high...
Investigation of the absorption mechanism of solubilized curcumin using caco-2 cell monolayers.
Curcumin is a bioactive compound with poor oral bioavailability. Low water solubility and rapid metabolism are two known limiting factors, but the absorption mechanism of solubilized curcumin remains...
This study describes the development and characterization of self-microemulsifying drug delivery systems (SMEDDS) in liquid and pellet forms that result in improved solubility, dissolution, and in viv...
