Cyclic Changes in Other Reproductive Organs

Natriuretic peptide rDNA

TASH Biotechnology

Shanghai TASH Biotechnology Co.,Ltd. specializes in peptide development on the basis of high technology. TASH Biotechnology are focusing on custom peptide synthesis, and the research, development...

Lyxumia

Lyxumia® is a glucagon-like peptide-1 receptor agonist (GLP-1 RA) for the treatment of patients with type 2 diabetes mellitus. GLP-1 is a naturally-occurring peptide hormone that is re...

Metabotropic Glutamate Receptor 4 (mGluR4)

Metabotropic glutamate receptor 4 is a protein that in humans is encoded by the GRM4 gene. Together with GRM6, GRM7 and GRM8 it belongs to group III of the metabotropic glutamate receptor famil...

Theradiag receives CE mark approval for anti-CCP in vitro diagnostic kit

Theradiag has received a CE mark approval for its anti cyclic citrullinated peptide (anti-CCP) in vitro diagnostic (IVD) kit in rheumatoid arthritis.

Casting out myeloma kidney

A University of Alabama team has developed a cyclic peptide that can treat cast nephropathy, a common renal complication of multiple myeloma. The next step is optimization of the peptide for oral avai...

Phage Display-directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication

Ra materials

Ra Pharma is emerging from stealth mode two years after securing a $27M A round to build its cyclic peptide platform, which generates molecules containing both natural and modified, unnatural amino ac...

RaPID results

A Japanese team has provided new structural insights into the function of a conserved class of drug transporters. The researchers are collaborating with PeptiDream to develop cyclic peptide inhibitors...

Ra, Merck in cyclic peptide deal

Ra Pharmaceuticals Inc. (Cambridge, Mass.) partnered with Merck & Co. Inc. (NYSE:MRK) to develop modified cyclic peptides that target multiple undisclosed protein targets selected by Merck for undiscl...

Allosteric activation of exopolysaccharide synthesis through cyclic di-GMP-stimulated protein–protein interaction

Biofilm formation allows pathogenic bacteria to evade detection by the immune system. The second messenger cyclic di-GMP bridges protein subunits of the poly-GlcNAc synthesis machinery to stimulate sy...

Enzyme that acts as innate immunity sensor

Two studies by researchers at UT Southwestern Medical Center could lead to new treatments for lupus and other autoimmune diseases and strengthen current therapies for viral, bacterial, and parasitic i...

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities.

OBJECTIVE: /st> Anti-citrullinated protein antibodies (ACPA) and anti-cyclic citrullinated peptide (anti-CCP) antibodies are a hallmark of rheumatoid arthritis and are believed to play a role in disea...

Is serum anti-cyclic citrullinated peptide level useful in the diagnosis of rheumatoid arthritis?

To find out whether serum level of anti-cyclic citrullinated peptides (anti-CCP) could be useful in the diagnosis of rheumatoid arthritis (RA).

Serum anti-cyclic citrullinated peptide antibodies may predict disease activity in rheumatoid arthritis.

To define the relationship between serum anti-cyclic citrullinated peptide antibodies (anti-CCP) and disease activity, and to construct a new disease activity index by using anti-CCP in rheumatoid art...

Anti-cyclic citrullinated peptide antibodies and rheumatoid factor sera titers in leprosy patients from Mexico.

Leprosy offers a broad spectrum of altered immunological sceneries, ranging from strong cell-mediated immune responses seen in tuberculoid leprosy (TT), through borderline leprosy (BB), to the virtual...

Familial mediterranean Fever presenting as anti-cyclic citrullinated Peptide antibody negative palindromic rheumatism.

A 64-year-old Egyptian man who resides in the United States presented to the rheumatology clinic with 6 months history of episodic recurrent pauci-arthritis along with constitutional symptoms. His Med...