Search Results for "Cyclophosphamide For Acute Gvhd"
Original Source: Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer
RATIONALE: Giving low doses of chemotherapy, such as fludarabine, and radiation therapy before a donor bone marrow or stem cell transplant helps stop the growth of cancer cells. It also stops the patient's immune system from rejecting the donor's stem cells. The donated stem cells may replace the patient's immune system and help destroy any remaining cancer cells (graft-versus-tumor effect). Sometimes the transplanted cells from a donor can also make an immune response against...
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SIR/TAC combination more effective in preventing GVHD after allogeneic blood cell transplantation
Researchers at Moffitt Cancer Center have conducted a clinical trial aimed at preventing graft vs. host disease (GVHD) in patients who have received hematopoietic (blood) cell transplants (HCT). The s...
[News] Chemokine receptor blockade in graft-versus-host disease
In a phase 1/2 trial, 35 high-risk patients with blood cancer who underwent reduced-intensity allogeneic stem-cell tranplantation who took the CCR5 chemokine receptor blocker maraviroc had lower rate...
Researchers test drug combinations to prevent graft vs. host disease
Researchers at Moffitt Cancer Center have conducted a clinical trial aimed at preventing graft vs. host disease (GVHD) in patients who have received hematopoietic (blood) cell transplants (HCT). The s...
Biomarkers for acute GVHD: can we predict the unpredictable?
Prognosis of grade 3–4 acute GVHD continues to be dismal
Acute gut GVHD in children: does skin involvement matter?
Moffitt Cancer Center researchers test drug combinations to prevent graft vs. host disease
(H. Lee Moffitt Cancer Center & Research Institute) Researchers at Moffitt Cancer Center have conducted a clinical trial aimed at preventing graft vs. host disease (GVHD) in patients who have received...
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Disbalance of Th1 and Th17 can lead to inflammatory diseases and autoimmunity. Acute graft-versus-host disease (GVHD) is now considered as a compound and dysregulated immune response. Both Th1 and Th1...
We retrospectively analyzed the association between anti-host isohemagglutinin (IH) production and the development of acute GVHD. Of 189 patients who received minor or major/minor ABO-incompatible hem...
High-dose cyclophosphamide for graft-versus-host disease prevention.
PURPOSE OF REVIEW: Administration of high-dose cyclophosphamide after transplantation inhibits both graft rejection and graft-versus-host disease (GvHD) in mouse models of allogeneic blood or marrow t...
Graft-versus-Host Disease (GvHD) - an update : Part 2: Prognosis and therapy of GvHD.
Graft-versus-host disease (GvHD) remains one of the major complications after allogeneic stem cell transplantation (SCT) and is responsible for morbidity, mortality and decrease in quality of life of...
Expression of α4β7 integrin on memory CD8(+) T cells at the presentation of acute intestinal GVHD.
Acute intestinal GVHD remains a major source of morbidity after allogeneic hematopoietic cell transplantation (HCT). α4β7 integrin is a cell surface molecule that mediates lymphocyte trafficking to...
