DIHYDROTETRABENAZINE BINDING TO RAT STRIATAL TISSUE Pages on BioPortfolio:

BioPortfolio - Pathology
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Results from other life science and pharmaceutical sites:

Pharmacokinetics of [18F]Fluoroalkyl Derivatives of ...
Rat studies were done using 200–300 g Sprague-Dawley rats (Charles Rivers, .... Tissue time vs. radioactivity curves for striatum and cerebellum regions of
..... 1997]; Binding of alpha-dihydrotetrabenazine to the vesicular monoamine
...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1905841/...

Striatal Dopaminergic and Serotonergic Markers in Human Heroin Users
DiChiara 1995) whereas striatal tissue dopamine levels are reduced in human .... 1996c), VMAT2 by radioligand binding (ten point [3H]dihydrotetrabenazine ....
with protein levels increased in rat "striatum" (the rodent counterpart of ...
http://www.nature.com/npp/journal/v24/n5/full/1395617a.html...

Characterization of Optically Resolved 9-fluoropropyl ...
Frozen rat brains were purchased from Pel-Freez (Invitrogen, ... The brain tissue homogenates were prepared in 50 mM Hepes, pH 7.5 and 0.32 M sucrose.
..... Albin R, Koeppe R. Rapid loss of striatal VMAT2 binding associated with
onset of Lewy ..... Binding of alpha-dihydrotetrabenazine to the vesicular
monoamine ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1919419/...

Journal of Cerebral Blood Flow & Metabolism - Kinetic Evaluation ...
Tissue heterogeneity may also play a role in the lack of fit of the ..... marker for the visualization of dopaminergic denervation in the rat striatum. ... (1986
) [3H]Dihydrotetrabenazine binding to bovine striatal synaptic vesicles. ...
http://www.nature.com/jcbfm/journal/v16/n6/full/9590154a.htm...

Quantitative autoradiography of the rat brain vesicular monoamine ...
The binding of [3H]dihydrotetrabenazine, a specific ligand of the monoamine ... 0.66 x 10(-3) s-1) were similar to those previously observed on tissue
homogenates. ... noradrenaline in the striatal fissure and in the
paraventricular and ...
http://www.ncbi.nlm.nih.gov/pubmed/2622531...

Neuropsychopharmacology - Human Methamphetamine Pharmacokinetics ...
Protein concentrations in rat striatal tissue homogenates were ..... density of the vesicular monoamine transporter and dihydrotetrabenazine binding sites. ...
http://www.nature.com/npp/journal/v34/n11/full/npp200973a.ht...

Pharmacokinetics of [(18)F]fluoroalkyl derivatives of ...
The specific binding and regional brain pharmacokinetics of new ... In the rat ... specific binding in the striatum than either (+)-[(11)C]dihydrotetrabenazine
... Tissue Distribution; Vesicular Monoamine Transport Proteins/metabolism* ...
http://www.ncbi.nlm.nih.gov/pubmed/17383572...

NIDA - Director's Report - September, 2006
22 Jul 2008 ... Brain Tissue Lipidomics: Direct Probing Using Matrix-Assisted ..... Test compounds were assessed in several assays including: a) inhibition of [(3)H]
dihydrotetrabenazine binding, .... from co-transfected mammalian cells and rat
striatum. These results reveal that striatal non-alpha(7) nicotinic ...
http://www.nida.nih.gov/DirReports/DirRep906/DirectorReport1...

[3H]dihydrotetrabenazine, a new in vitro monoaminergic probe for ...
[3H]Dihydrotetrabenazine binding in rat brain was stable after 72 h at 22 degrees C ... Animals; Binding Sites; Brain/metabolism*; Corpus Striatum/
metabolism ... Tetrabenazine/pharmacokinetics; Tissue Distribution. Substances:
...
http://www.ncbi.nlm.nih.gov/pubmed/3346671...

Journal of Cerebral Blood Flow & Metabolism - In vivo measurement ...
The intact striatum was used as an internal control condition for each animal. ... throughout the various tissue components and the nonspecific binding of ....
Each rat was positioned in a stereotaxic headholder similar to that used in the
..... Frey K (1995) Binding of alpha-dihydrotetrabenazine to the vesicular ...
http://www.nature.com/jcbfm/journal/v27/n7/full/9600446a.htm...

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