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Search Results for "Dana Farber Xl147"

05:26 EDT 21st May 2013 | BioPortfolio

Original Source: Study of the Safety and Pharmacokinetics of XL147 in Adults With Solid Tumors or Lymphoma

The purpose of this study is to evaluate the safety and tolerability of XL147 in subjects with solid tumors or lymphoma. XL147 is a new chemical entity that inhibits PI3 Kinase. Inactivation of PI3K has been shown to inhibit growth and induce apoptosis (programmed cell death) in tumor cells.

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Dana-Farber study shows newly isolated 'beige fat' cells could help fight obesity

(Dana-Farber Cancer Institute) Scientists at Dana-Farber Cancer Institute have isolated a new type of energy-burning fat cell in adult humans which they say may have therapeutic potential for treating...

Dana-Farber Cancer Institute to support BrainStorm's phase 2 ALS trial

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(Dana-Farber Cancer Institute) Dana-Farber scientists have found that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted...

OMNI Health Media Develops Cancer Social Media Platform for Dana-Farber Cancer Institute

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GNS joins forces with Dana-Farber, Mount Sinai to build myeloma computer models

GNS Healthcare has partnered with Dana-Farber Cancer Institute (Dana-Farber) and Mount Sinai School of Medicine (Mount Sinai) to build a computer model of multiple myeloma.

A male contraceptive pill in the making?

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New tool determines leukemia cells' 'readiness to die,' may guide clinical care

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The frequency and management of asparaginase-related thrombosis in paediatric and adult patients with acute lymphoblastic leukaemia treated on Dana-Farber Cancer Institute consortium protocols.

The optimal management of asparaginase-associated thrombotic complications is not well-defined. We report the features, management and outcome of paediatric (ages 0-18 years) and adult (18-50 year...

Concordance and discordance in tumor genomic profiling.

Impact of treatment-related cardiac toxicity on lymphoma survivors: an institutional approach for risk reduction and management.

Despite improvements in treatment and overall survival rates, survivors of lymphoma may have long-term and late effects. Given the immense risk for cardiac disease after treatment for Hodgkin lymphoma...

Clinical significance of coagulation studies in predicting response to activated recombinant Factor VII in cardiac surgery patients.

Renal disease appears not to affect carcinogenesis in CD151-null mice.

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