Daptomycin

Aortic Dissection

Aortic Regurgitation

Aortic Stenosis

Abdominal Aortic Aneurysms AAA

Early Daptomycin Use May Help in MRSA Bacteremia

Early daptomycin use may improve outcomes in methicillin-resistant Staphylococcus aureus (MRSA) bacteremia when the vancomycin minimal inhibitory concentration (MIC) is above 1 mcg/L. Reuters Health...

Daptomycin treats S. aureus bacteremia without nephrotoxicity

NEW YORK (Reuters Health) - Daptomycin, with or without beta-lactams, controls Staphylococcus aureus bacteremia without worsening renal dysfunction, registry data suggest.

Trius patent allowed for tedizolid-daptomycin bacteremia combo

On the eve of Trius Therapeutics' pursuit of US FDA approval for the antibiotic tedizolid phosphate, the San Diego-based company continues to expand the potential market for its drug candidate with p...

Inflatable Aortic Valve Reduces Aortic Regurgitation

An innovative transcatheter aortic valve system virtually eliminates aortic regurgitation with no vascular complications.

Surgical treatment of aortic valve disease

Tirone David expertly reviews the surgical repair and replacement of the aortic valve. Patient selection for aortic valve-sparing operations, bioprosthetic or mechanical valve insertion, pulmonary aut...

Gene Associated With Inflammation In The Aorta Could Lead To Abdominal Aortic Aneurysm

A gene that contributes to cancer and cardiovascular development may be the cause of swelling in the most common type of aortic aneurysm, and could be the key to treatment. This new study, published i...

Patients With Severe Aortic Stenosis Report Improved Quality Of Life Following Transcatheter Aortic Valve Implantation

Transcatheter aortic valve implantation (TAVI) leads to meaningful improvements in health-related quality of life in patients with severe aortic stenosis that are maintained for at least 1 year, accor...

Genetic variation doubles risk of aortic valve calcification

Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a bl...

Manipulation of kynurenine pathway for enhanced daptomycin production in Streptomyces roseosporus.

Daptomycin is a cyclic lipopeptide natural product produced by Stretptomyces roseosporus, displaying good bactericidal activity against a wide range of Gram-positive pathogens. Daptomycin contains a 1...

Six cases of daptomycin non-susceptible Staphylococcus aureus bacteremia in Singapore.

We report the first six cases of daptomycin-non-susceptible Staphylococcus aureus infections from Singapore. These strains were rapidly isolated after bacteremic patients were switched to daptomycin f...

Variability of pharmacokinetic parameters in patients receiving different dosages of daptomycin: is therapeutic drug monitoring necessary?

Pharmacokinetic studies of daptomycin in septic patients indicate that pharmacokinetic parameters may be altered. The purpose of this clinical investigation is to determine the pharmacokinetics of dap...

Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery.

ABSTRACT: We present a case of a 77-year old female who had undergone a coronary artery bypass grafting with an aortic valve replacement and developed three month later a Methicillin-Resistant Staphyl...

A rare cause of pulmonary infiltrates one should be aware of: a case of daptomycin-induced acute eosinophilic pneumonia.

We report a 69-year-old patient who developed fever and dyspnea 3 weeks after the initiation of daptomycin therapy for spondylodiscitis with lumbar epidural and bilateral psoas abscesses due to ampic...