Search Results for "Davis Beirut Reaction"
Original Source: The Davis-Beirut Reaction: N(1),N(2)-Disubstituted-1H-Indazolones via 1,6-Electrophilic Addition to 3-Alkoxy-2H-Indazoles.
A variety of electrophiles (anhydrides, acid chlorides, carbonochloridates, sulfonyl chlorides, and alkyl bromides) react with 3-methoxy-2H-indazole (1a), benzoxazin[3,2-b]indazole (1d), and oxazolino[3,2-b]indazole (1e) - substrates available by the Davis-Beirut reaction - to yield a diverse set of N(1),N(2)-disubstituted-1H-indazolones. With certain electrophiles, an AERORC (Addition of the Electrophile, Ring Opening, and Ring Closure) process on indazole 1d results in indazoloindazolone formation...
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Label-assisted mass spectrometry for the acceleration of reaction discovery and optimization
The development of new reaction methodology is a core activity for organic chemists, but the process can be slow and can rely on serendipity. Here, a reaction discovery platform is described that reli...
New insights into how the most iconic reaction in organic chemistry really works
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UC Davis study finds that above-normal weight alone does not increase the short-term risk of death
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PCI Appoints John Davis, PE, to Board
Raleigh, NC (PRWEB) March 14, 2013 PCI, a leading provider of calibration and maintenance services to the Life Sciences industry is pleased to announce the recent appointment of John Davis, PE, t...
Single-DNA images from UC Davis give clues to breast cancer
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UC Davis study links low wages with hypertension, especially for women and younger workers
(University of California - Davis Health System) Workers earning the lowest wages have a higher risk of hypertension than workers with the highest wages, according to new research from UC Davis.
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(University of California - Davis Health System) New research from the UC Davis Comprehensive Cancer Center, published in the Journal of Surgical Research, may help clinicians determine which patients...
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(University of California - Davis Health System) A team of UC Davis investigators has found that a genetic mutation may play an important role in the development of prostate cancer.
Matching PubMed Articles
The Davis-Beirut reaction, which provides an efficient synthesis of 2H-indazoles and, subsequently, indazolones, is shown to proceed rapidly from o-nitrosobenzaldehyde and primary amines under both ac...
A variety of electrophiles (anhydrides, acid chlorides, carbonochloridates, sulfonyl chlorides, and alkyl bromides) react with 3-methoxy-2H-indazole (1a), benzoxazin[3,2-b]indazole (1d), and oxazolino...
A number of novel benzo-1,3-dioxolo-, benzothiazolo-, pyrido-, and quinolino-fused 5H-benzo[d]pyrazolo[5,1-b][1,3]-oxazines and 1H-pyrazoles were synthesized utilizing an easy and effective N,N-bond f...
Efficient Syntheses of the Unknown Quinolino2,3-ccinnolines; Synthesis of Neocryptolepines.
A facile, efficient, three-step protocol for the synthesis of the unknown quinolino[2,3-c]cinnoline 5 is introduced. In addition, a new approach for the preparation of the biologically active neocrypt...
We report the alkoxylation of methyl-substituted quinoxalino[2,3-c]cinnolines to give acetals and orthoesters in high yields. Routes to the precursors of this alkoxylation reaction as well as other qu...
