Search Results for "Dcis Recurrence After Mastectomy"

11:16 EST 25th January 2015 | BioPortfolio

Original Source: Analyzing the Risk of Recurrence after Mastectomy for DCIS: A New Use for the USC/Van Nuys Prognostic Index.

BACKGROUND: Patients with ductal carcinoma in situ (DCIS) who are treated with mastectomy seldom recur locally or with metastatic disease. When patients with DCIS recur with invasive cancer, they are upstaged and their lives are threatened. We questioned whether histopathologic data could be used to predict these infrequent events. METHODS: We reviewed a prospective database of 1,472 patients with pure DCIS. All patients were scored from 4 to 12 using the USC Van Nuys Prognostic Index, an algorithm based on...

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I Have DCIS, Should I Have a Bilateral Mastectomy?

By ROBERT McNutt, MD Benefit: There is none. No women with DCIS have been included in a randomized controlled trial. Harm: Cosmetic outcomes are unclear; Second operations to fix the cosmetic outcome ...

20 Years Later, Radiation Protects Against DCIS Recurrence

Rates of recurrence of ductal carcinoma in situ (DCIS) after breast-conserving surgery (BCS) remain lower 20 years after radiotherapy, according to results from the SweDCIS Trial. Reuters Health Inf...

Multigene test can predict risk of disease recurrence for women with ductal carcinoma in situ

In a press conference at SABCS 2014, Prof Rakovitch discusses the use of a multigene test called Oncotype DX DCIS Score (DCIS Score) as a predictor of risk of disease recurrence for patients with d...

Recurrence risk could be predicted by a multigene test in ductal carcinoma breast cancer

Prof Rakovitch talks to ecancertv at SABCS 2014 about the use of a multigene test called Oncotype DX DCIS Score (DCIS Score) which seeks to predict of risk of disease recurrence for patients with duct...

DCIS Test Identifies Patients With Low Recurrence Risk

A new Oncotype test identifies patients with ductal carcinoma in situ (DCIS) who are at low risk for recurrence and for the development of invasive breast cancer. Medscape Medical News

Top stories in health and medicine, December 17, 2014

From MedPage Today: Gene Test Has Promise for Nailing DCIS Recurrence Risk. A multigene panel predicted recurrence risk in ductal carcinoma in situ (DCIS), according to a population-based study. Docs...

SABCS 2014: Multigene test can predict risk of disease recurrence for women with ductal carcinoma in situ

A multigene test called Oncotype DX DCIS Score (DCIS Score) was validated as a predictor of risk of disease recurrence among women treated with breast-conserving surgery alone for ductal carcinoma in ...

Oncotype DX DCIS Score Represents Breakthrough in Personalizing Treatment of Pre-Invasive Breast Cancer

Genomic Health Inc. has announced positive results from the second large clinical validation study of Oncotype DX in patients with a pre-invasive form of breast cancer known as DCIS (ductal carcinoma ...

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Impact of Breast Reconstruction on the Decision to Undergo Contralateral Prophylactic Mastectomy.

In the last decade, there has been increasing use of contralateral prophylactic mastectomy (CPM) in patients with unilateral breast cancer and ductal carcinoma-in-situ (DCIS) undergoing mastectomy. Al...

The current clinical value of the DCIS Score.

The management of ductal carcinoma in situ (DCIS) can be controversial. Widespread adoption of mammographic screening has made DCIS a more frequent diagnosis, and increasingly smaller, lower-grade les...

Smoking and breast cancer recurrence after breast conservation therapy.

Background. Prior studies have shown earlier recurrence and decreased survival in patients with head and neck cancer who smoked while undergoing radiation therapy. The purpose of the current study was...

Contralateral Prophylactic Mastectomy After Unilateral Breast Cancer: A Systematic Review and Meta-analysis.

To examine whether contralateral prophylactic mastectomy (CPM) is associated with improved survival, incidence of contralateral breast cancer (CBC), and recurrence in patients with unilateral breast c...

Molecular Pathology: SY18-1 MOLECULAR PROFILING OF BREAST DUCTAL CARCINOMA IN-SITU.

Ductal carcinoma in-situ (DCIS) is a precursor of invasive breast carcinoma (IBC) and highly heterogeneous with variable presentation, morphology, and behavior. Although significant advance has been m...

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