Eosinophilia

Pulmonary

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Pulmonary Hypertension

Pulmonary Embolism

The Prevalence of Esophageal Eosinophilia and EoE

How common is esophageal eosinophilia in the presence of eosinophilic esophagitis? This new study explains. Alimentary Pharmacology & Therapeutics

Fluticasone improves histologic eosinophilia in esophagitis

(HealthDay) -- Swallowing aerosolized fluticasone improves histologic eosinophilia but does not improve dysphagia symptoms in adults with eosinophilic esophagitis (EoE), according to a study published...

Decitabine Approved for Elderly AML in Europe

Although rejected earlier this year by regulators in the United States, decitabine has been okayed by the European Commission. International Approvals

[News] Low-dose decitabine for myelodysplastic syndrome

Low-dose regimens of subcutaneous decitabine could be a promising option for patients with low-risk or intermediate-1-risk myelodysplastic syndrome (MDS), according to a recent randomised phase 2 stu...

Miocardin in Pulmonary arterial hypertension

So, what is pulmonary hypertension (PH) is an increase in blood pressure in the pulmonary artery, pulmonary vein, or pulmonary [...]

An interleukin-33 gene polymorphism is a modifier for eosinophilia in rats

A Bullish Argument For Cyclacel's Sapacitabine And Seamless

By Brian Thomson:Cyclacel Pharmaceuticals (CYCC) is currently developing Sapacitabine, an oral nucleoside analogue which interferes with DNA synthesis, for the treatment of elderly AML and MDS. Althou...

Long-term follow-up of FIP1L1-PDGFRA-mutated patients with eosinophilia: survival and clinical outcome

Hypereosinophilic syndrome associated with simultaneous intracardiac thrombi, cerebral thromboembolism and pulmonary embolism.

The hypereosinophilic syndrome (HES) is a subcategory of idiopathic eosinophilia which is characterized by marked unexplained eosinophilia and evidence of tissue eosinophilia which leads to eosinophil...

An HPLC-MS/MS method for simultaneous determination of decitabine and its valyl prodrug valdecitabine in rat plasma.

A simple and sensitive HPLC-MS/MS method was developed and validated for the simultaneous determination of decitabine and valdecitabine in rat plasma. The analytes were separated on a C(18) column (15...

Persistent Eosinophilia - Differential Diagnosis and Work-up.

The differential diagnosis of eosinophilia is broad and constitutes a major challenge for both, the general practitioner and the hematologist. Whereas in developing countries secondary eosinophilia is...

Pulmonary ascariasis: two cases in Austria and review of the literature.

Ascariasis is the most common helminthic infection, with an estimated worldwide prevalence of 25%. The estimated mortality ranges from 0.8 to 1%. Second stage larvae pass through the intestinal wall a...

Decreased incidence of febrile episodes with antibiotic prophylaxis in the treatment of decitabine for myelodysplastic syndrome.

We analyzed the role of antibiotic prophylaxis during decitabine treatment for MDS. The primary endpoint was the incidence of febrile episodes. The total number of decitabine cycles given to 28 patien...