Search Results for "Diclofenac Suppository Clinical Studies"
Original Source: Diclofenac for the Prevention of Post-ERCP Pancreatitis in Higher Risk Patients
Inflammation of the pancreas (pancreatitis) is an uncommon but potentially serious complication of endoscopic retrograde cholangiopancreatography (ERCP), a specialized endoscopic examination of the ducts draining the liver and pancreas. Although many different strategies have been tried and studied in attempts to reduce this risk, few have been shown to make a significant difference. Those that have are either very expensive, difficult to administer, or both. Diclofenac,...
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Electrophysiologic Studies EPS
Electromyography and nerve conduction velocity studies
Clinical trials involving new drugs are commonly classified into four phases. Each phase of the drug approval process is treated as a separate clinical trial. The drug-development process will norma...
p38 mitogen activated protein kinase MAPK Inhibitors
The next generation of p38 mitogen-activated protein kinase (MAPK) inhibitors has reached clinical proof-of-concept studies in phase II in a broad range of indications. While the previous generation o...
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Diclofenac, which is listed on the essential-medicine lists of 74 countries, increased the risk of cardiovascular events between 38% and 63% in different studies. The increased risk with diclofenac wa...
Higher heart risk with diclofenac than other NSAIDs
Diclofenac is associated with a "consistent but small" increase in the risk of cardiovascular side effects...
Type: Original PaperA simple high-performance liquid chromatographic method for simultaneous determination of ethylenediaminetetraacetic acid (EDTA), sorbic acid, and diclofenac sodium was developed a...
Iroko Pharmaceuticals, LLC, a Philadelphia-based pharmaceutical company focused on the development and commercialization of innovative therapeutic products, today announced...
Acute Pain Yields to Lower-Dose Diclofenac
(MedPage Today) -- FORT LAUDERDALE, Fla. - Lower-dose submicron particle diclofenac offered good pain control compared with placebo, researchers reported here.
Global use of diclofenac widespread, despite CV risks
Diclofenac use remains widespread globally despite the drug’s known cardiovascular risks, a study in PLOS Medicine has shown (online 12 February 2013). Researchers looked at cardiovascular risk...
An international study has suggested that a painkiller that increases the risk of heart attack and stroke may be being overprescribed. Prescribing practices were examined in 15 countries, includi...
Iroko reports Phase III data for submicron diclofenac
Iroko Pharmaceuticals LLC (Philadelphia, Pa.) said thrice-daily lower dose submicron diclofenac met the primary endpoint of reducing mean WOMAC pain subscale scores from baseline to week 12 vs. placeb...
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PURPOSE: We aimed to compare the analgesic effects of low-dose intravenous ketamine with the effects of diclofenac suppositories in acute postoperative pain management in women undergoing gynecologic...
PURPOSE: We compared the efficacy and side effects of diclofenac and a topical eutectic mixture of local anesthetics (EMLA) for pain relief after hemorrhoidectomy. METHODS: Ninety patients, nominated...
BACKGROUND: We compared the analgesic efficacy of diclofenac-acetaminophen combination with diclofenac-tramadol combination to optimize multimodal post-operative analgesia in women undergoing caesarea...
Aim. To determine the effects of hyoscine-N-butyl bromide (HBB) rectal suppository on labor progress in primigravid women. Methods. A randomized double-blind placebo-controlled clinical trial was carr...
OBJECTIVE: Diclofenac is an effective and well-tolerated nonsteroidal anti-inflammatory drug (NSAID) frequently used in the treatment of acute pain. Marketed formulations for parenteral administration...
