Digoxin Globulin ovine Fab GSK

Digoxin Globulin ovine Fab Protherics

Digoxin Globulin ovine Fab Roche

Ventricular rate control

Sustained high ventricular rates during persistent or permanent AF can lead to a deterioration in left ventricular function, hence the requirement for rate control. Historically, digoxin has been us...

Re-analysis of digoxin data yields conflicting results

Debate continues over the use of digoxin in atrial fibrillation (AF). A recent suggestion that the drug’s use should be reassessed because of safety concerns is not supported by a further analysis...

Increased Mortality With Digoxin in AF

The senior author of a new AFFIRM analysis says the results should make doctors think hard about whether to prescribe digoxin for AF patients, especially if they don't also have heart failure. Heart...

ACC: Digoxin Drops HF Admissions (CME/CE)

SAN FRANCISCO (MedPage Today) -- Digoxin could be part of the solution to high hospitalization rates in heart failure, researchers suggested in a subanalysis of the DIG trial.

Another Strike for Digoxin in AF: Mortality Goes Up

Mortality, but not hospitalization, went up for patients with AF (but without heart failure) taking digoxin in a large patient cohort, echoing observational findings from the AFFIRM trial. Heartwire

Digoxin associated with reduced hospital admissions

Digoxin reduces hospital admissions among older patients with chronic systolic heart failure, according to data from a placebo-controlled trial (American Journal of Medicine, online 13 March 2013)....

Digoxin may increase deaths in patients with atrial fibrillation

NEW YORK (Reuters Health) - People with atrial fibrillation were more likely to die within several years if they had been prescribed digoxin, in an observational study.

Digoxin Found To Be Safe Despite Recent Reports

A study published in the European Heart Journal found no evidence that digoxin increases mortality in patients with atrial fibrillation (AF), the opposite of results just published by another group in...

Digoxin for atrial fibrillation questioned

Experts are calling into question the widespread use of digoxin for atrial fibrillation, in the wake of findings linking the drug to increased mortality.

Interference of hawthorn on serum digoxin measurements by immunoassays and pharmacodynamic interaction with digoxin.

Abstract Context.-Hawthorn is an herb indicated for treating cardiac illness. Because a patient taking digoxin may also take hawthorn, we investigated potential interference of hawthorn in serum digox...

In Vitro P-Glycoprotein Interactions and Steady-State Pharmacokinetic Interactions Between Tolvaptan and Digoxin in Healthy Subjects.

Interactions between tolvaptan and digoxin were determined in an open-label, sequential study where 14 healthy subjects received tolvaptan 60 mg once daily (QD) on days 1 and 12 to 16 and digoxin 0.25...

In vitro selection and characterization of deoxyribonucleic acid aptamers for digoxin.

The low therapeutic index of digoxin necessitates careful monitoring of its serum levels. Most of digoxin immunoassays suffer from interferences with digoxin-like immunoreactive substances. Since apta...

Evaluation of the pharmacokinetic interaction after multiple oral doses of linagliptin and digoxin in healthy volunteers.

The aim of this study was to investigate whether multiple doses of the oral and highly selective dipeptidyl peptidase-4 inhibitor linagliptin affect the steady-state pharmacokinetics of the P-glycopro...

Hepatic interaction between quinidine and digoxin: Role of inhibition of sinusoidal Na(+)/K(+) ATPase digoxin binding.

The mechanism by which quinidine affects hepatic digoxin pharmacokinetics remains controversial. Here, we study the role of displacement of digoxin from hepatic sinusoidal binding sites by quinidine....