Search Results for "Dihydroartemisinin Store"
Original Source: The pharmaceutical death-ride of dihydroartemisinin.
ABSTRACT: In the 2010 second edition of WHO's guidelines for the treatment of malaria, the relatively new fixed dose combination dihydroartemisinin-piperaquine is included as one of the recommended artemisinin combination therapies. However, experimental testing demonstrates that, due to its intrinsic chemical instability, dihydroartemisinin is not suitable to be used in pharmaceutical formulations. In addition, data show that the currently available dihydroartemisinin preparations fail to meet the internat...
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New malaria drug ready for launch
Eurartesim, the first artemisinin combination therapy (ACT) approved in Europe to treat uncomplicated malaria, is being prepared for launch in several countries. Eurartesim, (dihydroartemisinin pipera...
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Sigma-tau's Antimalarial Awarded "Project of the Year" 2011 by Medicines for Malaria Venture
NEW DELHI, November 27, 2012 /- The project team for Eurartesim®, dihydroartemisinin-piperaquine (DHA-PQP), the first novel chemical entity developed by Sigma-Tau was awarded Medicines for Mala...
Roll-Out Of New Anti-Malaria Drug, Eurartesim(R) Begun
Eurartesim(R) (dihydroartemisinin piperaquine: DHA-PQP), the first artemisinin combination therapy (ACT) approved by the European Medicines Agency (EMA) for the treatment of uncomplicated malaria, is...
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The pharmaceutical death-ride of dihydroartemisinin.
ABSTRACT: In the 2010 second edition of WHO's guidelines for the treatment of malaria, the relatively new fixed dose combination dihydroartemisinin-piperaquine is included as one of the recommended ar...
A series of dihydroartemisinin derivatives were synthesized via an aza-Michael addition reaction to a dihydroartemisinin-based acrylate and were evaluated for antiplasmodial and antitumor activity. Th...
Effect of the in vivo activity of dihydroartemisinin against Schistosoma mansoni infection in mice.
Dihydroartemisinin, formerly known as an antimalarial drug, is the main metabolite of the mother compound artemisinins, as well as of artemether and artesunate. It has been shown that the drug exhibit...
Recently, promising fasciocidal activities of artesunate and artemether were described in rats and sheep. Therefore, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed to...
The area cultivated with Artemisia annua for the extraction of the antimalarial compound artemisinin is increasing, but the environmental impact of this cultivation has not yet been studied. A sensiti...