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Search Results for "Dissociative Seizures Topiramate"

08:41 EDT 19th June 2013 | BioPortfolio

Original Source: Hormonal alterations following seizures.

Postictal increases in prolactin (PRL), luteinizing hormone, and follicle-stimulating hormone have been recorded in patients with both generalized tonic-clonic and partial seizures. Elevations of PRL and luteinizing hormone were seen immediately and at 20minutes after generalized tonic-clonic seizures in male and female patients. Usually, PRL blood levels return to normal values within 1 hour. Previous studies have evaluated the utility of the transient increases in PRL, neuron-specific enolase, and S-100 p...

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Upsher-Smith Successfully Completes Phase III Study Of USL255 (Extended-Release Topiramate) For Adjunctive Treatment Of Epilepsy In Patients With Refractory Partial-Onset Seizures

MAPLE GROVE, Minn., May 22, 2013 /PRNewswire/ -- Upsher-Smith Laboratories, Inc. today announced the successful completion of its global Phase III clinical trial for USL255 (extended-release topi...

Study Of Non-Epileptic Seizures Has Surprising Results

A Loyola University Medical Center neurologist is reporting surprising results of a study of patients who experience both epileptic and non-epileptic seizures. Non-epileptic seizures resemble epilepti...

Pediatric Fever-Induced Seizures Reduced By Common Drug

Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last fr...

Topiramate in pregnancy may boost oral clefts risk

NEW YORK (Reuters Health) - Pooled data suggest that first-trimester use of topiramate monotherapy is associated with a small increased risk of cleft lip and cleft palate in offspring.

New Data on Seizures and Risk Factors in Pediatric ICH

Results show that seizures are very common at presentation in children and neonates with ICH and highlight the importance of EEG monitoring, which found a high incidence of subclinical seizures. Med...

New culprit for epileptic seizures: Some seizures arise in glial cells

A new study suggests that some seizures may originate in non-neuronal cells known as glia, which were long believed to play a mere supporting role in brain function.

Seizures Common in Pediatric Stroke (CME/CE)

(MedPage Today) -- Almost half of children with hemorrhagic stroke had seizures at presentation or within a week of onset, but two-thirds had no further seizures 2 years later, a prospective study sho...

Nimodipine reduces febrile seizures

Fever-induced childhood seizures, known as febrile seizures, can be terrifying for parents to witness. The full-body convulsions, which mostly affect children six months to five years old, can last fr...

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Efficacy of Topiramate as an Add-on Drug in Seizures in Indian Children-An Observational Study.

OBJECTIVE: To assess the efficacy of Topiramate as an add-on drug in the treatment of seizures in children of age group 0-12 years. METHODS: Fifty children of age 0-12 years with seizures viz. parti...

Retrospective analysis of the effectiveness of first-line antiepileptic drugs for generalized onset and unclassified epileptic seizures in Chinese children.

BACKGROUND AND PURPOSE: Based on the time until treatment failure, we retrospectively analyzed 389 children to compare the long-term effectiveness of first-line antiepileptic drugs (AEDs) in children...

Topiramate reduces blood-brain barrier disruption and inhibits seizure activity in hyperthermia-induced seizures in rats with cortical dysplasia.

We investigated the effects of topiramate (TPM), a novel broad spectrum anticonvulsant, on seizure severity, survival rate and blood-brain barrier (BBB) integrity during hyperthermic seizures in rats...

Effects of topiramate on diabetes mellitus induced by streptozotocin in rats.

Topiramate currently approved for marketing as antiepileptic drug also possesses anti-diabetic activity. The aim of this study was to determine the antidiabetic effect of topiramate in a rat model of...

A simple, rapid and specific method for measurement of topiramate in human plasma by LC-MS/MS employing automated solid-phase extraction techniques: Application for bioequivalence study.

A rapid liquid chromatography coupled with ESI tandem mass spectrometry (LC-MS/MS) method was developed and validated for the quantification of topiramate in heparinized human plasma. The plasma sampl...

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