Search Results for "Does Sleeplessness Affect Connexin 43"
Original Source: Sleep deprivation and sleep recovery modifies connexin36 and connexin43 protein levels in rat brain.
Gap junctional communication is mainly mediated by connexin36 and connexin43 in neurons and astrocytes, respectively. It has been suggested that connexin36 allows electrical coupling between neurons whereas connexin43 participates in several process including release of ATP. It was recently reported that blockage of gap junctional communication mediated by connexin36 can disrupt the sleep architecture of the rat. However, there is no experimental approach about effects of sleep deprivation on connexins expr...
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Connexin 43 deficiency may protect against bed rest-associated bone loss
Mice lacking connexin 43, the most abundant gap junction protein in bone, have a decreased susceptibility to the effects of mechanical unloading on bone, US researchers report.Licensed from Medwire ne...
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Gap junctional communication promotes apoptosis in a connexin-type-dependent manner
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Connexins: Sensors and regulators of cell cycling.
It is nowadays well established that gap junctions are critical gatekeepers of cell proliferation, by controlling the intercellular exchange of essential growth regulators. In recent years, however, i...
Connexins, through gap junctional intercellular communication, are known to regulate many physiological functions involved in developmental processes such as cell proliferation, differentiation, migra...
Erythrokeratoderma variabilis (EKV) is characterized by fixed hyperkeratotic plaques and transient erythema. Mutations in the genes GJB3 and GJB4, which encode connexin (Cx)31 and Cx30.3, are associat...
Activation of astrocytes surrounding amyloid plaques is a hallmark of Alzheimer disease (AD) with consequences yet poorly understood. Astrocytes are characterized by a high level of intercellular comm...
Expression of Gap Junction Protein Connexin 43 in Bovine Urinary Bladder Tumours.
The aetiopathogenesis of urinary bladder tumours in cattle involves prolonged ingestion of bracken fern and infection by bovine papillomavirus types 1 or 2 (BPV-1/2). The oncogenic activity of BPV is...
