Maryland

Maryland, the US state on the mid-Atlantic coast, is hub of biotechnology institutions and companies. In 2005/2006 is was the 2nd best area globally for initiatives aimed at drawing and retaining bi...

Pfizer Profile 1007 study meets primary endpoint

Pfizer has announced positive results from Phase 3 Profile 1007 study evaluating Xalkori (crizotinib) in patients with anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NS...

Pfizer Announces Positive Results From Phase 3 Study PROFILE 1007 Evaluating XALKORI (crizotinib) In Previously Treated Patients With ALK-Positive Advanced Non-Small Cell Lung Cancer

Detailed Study Results to be Presented at an Upcoming Medical Congress NEW YORK--(BUSINESS WIRE)--Jun 19, 2012 - Pfizer Inc. announced today that the PROFILE 1007 study met its primary endpoint, demon...

EC approves Xalkori for NSCLC

The European Commission conditionally approved an MAA from Pfizer Inc. (NYSE:PFE) for Xalkori crizotinib to treat previously treated, advanced non-small cell lung cancer (NSCLC) in patients whose tumo...

Pfizer Announces Positive Results From Phase 3 Study PROFILE 1007 Evaluating XALKORI® ...

Detailed Study Results to be Presented at an Upcoming Medical Congress

Pfizer's Xalkori meets Phase III endpoint

Pfizer Inc. (NYSE:PFE) said Xalkori crizotinib met the primary endpoint of median progression-free survival (PFS) vs. investigator's choice of pemetrexed or docetaxel in the Phase III PROFILE 1007 tri...

Positive results from Phase 3 study PROFILE 1007 evaluating XALKORI® (crizotinib) in previously treated patients with ALK-Positive advanced NSCLC

Detailed study results to be presented...

Aspen Dental to inaugurate new office in Gallatin, TN on Feb. 21

Aspen Dental is proud to announce that a new Aspen Dental office is opening in Gallatin, TN on Thursday, Feb. 21. Located at 1007 Nashville Pike, the practice will provide dental services that range f...

Retraction: DNA demethylation in hormone-induced transcriptional derepression

Nature461, 1007–1012 (2009); doi:10.1038/nature08456.In this Letter, we claimed that hormone-regulated transcriptional control involves DNA demethylation mediated by MBD4. Subsequently, we corrected...

Erratum to: Journal of Computational Neuroscience, DOI 10.1007/s10827-010-0303-y and DOI 10.1007/s10827-010-0304-x.

Systemic lupus erythematosus induced by interferon β1 therapy in a patient with multiple sclerosis.

Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to a drug exposure. We report a 34-year-old woman with multiple sclerosis who developed, while being treated wit...

The Classic: On Loose Bodies in the Joint.

This Classic Article is a translation of the original work by Franz König, "Ueber freie Körper in den Gelenken" [On loose bodies in the joint]. Dtsch Z Chir. 1887;27: 90-109. available at DOI 10.100...

Another NOTCH for Cancer.

Erratum to: ACP, volume 33, issues 1, 3-4 and 5-6, 2010.