Dominant optic atrophy

Marijuana Cannabis

Autosomal Dominant

Optic Neuritis

Gastric atrophy

Mutations in NMNAT1 cause Leber congenital amaurosis with early-onset severe macular and optic atrophy

Josseline Kaplan, Jean-Michel Rozet and colleagues show that biallelic mutations in NMNAT1 cause an autosomal recessive form of Leber congenital amaurosis characterized by early-onset severe macular a...

Gray matter atrophy underlies PD subtypes

Patients with the postural instability gait difficulty subtype of Parkinson’s disease have marked gray matter atrophy relative to those with the tremor dominant subtype, shows research.

Optic atrophy 1 mediates mitochondria remodeling and dopaminergic neurodegeneration linked to complex I deficiency

WFS1 variants in Finnish patients with diabetes mellitus, sensorineural hearing impairment or optic atrophy, and in suicide victims

Researchers Regenerate Optic Nerve In Mice

Individuals blinded by optic nerve damage from glaucoma or trauma might be able to regain at least some visual function in the future after researchers have successfully regenerated the optic nerve in...

Atrophy in key region of brain associated with multiple sclerosis

Magnetic resonance imaging (MRI) measurements of atrophy in an important area of the brain are an accurate predictor of multiple sclerosis (MS), according to a new study published online in the journa...

Innovative Medical Marijuana Growing Product added to PotLocator.com Lineup

Tacoma, Washington (PRWEB) March 16, 2013 The medical marijuana industry's number one cannabis-based advertising portal for all medical marijuana dispensaries, board-certified marijuana doctors...

Cellphone Use May Reveal Your 'Dominant Brain'

By Alan Mozes HealthDay Reporter FRIDAY, May 17 (HealthDay News) -- New research suggests the dominant side of your brain may make the call on which ear you choose to use while talking...

Mouse models of dominant optic atrophy: What do they tell us about the pathophysiology of visual loss?

Dominant optic atrophy (DOA) is the most common inherited optic neuropathy affecting one in every 12,000 people. It presents with bilateral visual loss, central visual fields defects, colour vision di...

Juvenile glaucoma in propionic acidemia.

Propionic acidemia (PA) is a rare autosomal recessive disorder resulting from deficiency of the biotin-dependent enzyme propionyl-CoA carboxylase, which is necessary for the catabolism of branched cha...

Defective Mitochondrial Adenosine Triphosphate Production in Skeletal Muscle From Patients With Dominant Optic Atrophy Due to OPA1 Mutations.

OBJECTIVE: To assess whether impaired energy metabolism in skeletal muscle is a hallmark feature of patients with dominant optic atrophy due to several different mutations in the OPA1 gene. DESIGN: We...

Genomic deletions in OPA1 in Danish patients with autosomal dominant optic atrophy.

ABSTRACT: BACKGROUND: Autosomal dominant optic atrophy (ADOA, Kjer disease, MIM #165500) is the most common form of hereditary optic neuropathy. Mutations in OPA1 located at chromosome 3q28 are the pr...

Marijuana Exposure Opportunity and Initiation during College: Parent and Peer Influences.

Marijuana is the most prevalent illicit drug used by adolescents and young adults, yet marijuana initiation is rarely studied past adolescence. The present study sought to advance our understanding of...