Abbott

The 11th largest pharmaceutical company in the world, Abbott Laboratories generated sales of $16 billion in 2009 and has 90,000 employees. Within the medical device arm of the company, products of...

Urokinase Abbott

Synthesis and Release of Thyroid Hormones

Drug Delivery - news, views, blogs

Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals.  Drug delivery technologies are patent protected formulat...

The Top 10 Medical Device Companies

Medical devices are crucial to the process of diagnosis and treatment in modern medicine. Sales in this field reach billions of dollar a year, with Johnson & Johnson making $30 billion alone in...

Intestinal Levodopa-Carbidopa for Parkinson’s Reduced ‘Off’ Time

Phase III data on Abbott’s Duodopa were presented at the American Academy of Neurology.

Abbott Holding Steady For Long-Term Investments

By ValueMax:Abbott Laboratories (ABT) is currently one of the most appealing investments in the Big Pharma sector. Abbott continues to increase applications for its industry leading rheumatoid arthrit...

Abbott Challenges Biosimilar Legality

This from today's Xconomy. Abbott has filed a citizen's petition with the FDA to protect Humira by challenging the notion that the agency can refer to Abbott's Humira BLA filing. Their argument (poste...

Abbott's AbbVie spinout debuts

The AbbVie Inc. (NYSE:ABBV) pharmaceutical business spinout of Abbott Laboratories (NYSE:ABT) debuted on Wednesday as a separate public company. Abbott retains Abbott's name and houses the pharma's ge...

Abbott Laboratories Pre-Earnings: Nutritionals To Drive Growth

By Trefis: Abbott Labs (ABT) is scheduled to release its earnings for the first quarter of this year on April 17. This is the first earnings result after the company spun off its proprietary pharm...

TEXT-S&P may still cut Abbott Laboratories ratings

Overview -- U.S. diversified pharmaceutical company Abbott Laboratories intends to split off its global proprietary pharmaceutical operations into a separate company, to be named AbbVie, lea...

Abbott Laboratories to buy production facilities in Russia

The rumored Abbott Laboratories deal could be one of the top three largest acquisitions in the history of Russia’s pharmaceutical market. A source at the Federal Anti-monopoly Service of Russia has...

BRIEF-Abbott's Humira wins EU approval for new use

Nov 27 (Reuters) - Abbott Laboratories : * Abbott's Humira (adalimumab) approved in Europe for severe active pediatric

A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating.

The time-dependent local drug delivery from drug-eluting stents (DES) plays a critical role in reducing restenosis in intravascular stenting. To better understand the basic mechanism of drug release f...

Abbott Physicochemical Tiering (APT)-A unified approach to HTS triage.

The selection of the highest quality chemical matter from high throughput screening (HTS) is the ultimate aim of any triage process. Typically there are many hundreds or thousands of hits capable of m...

Exploration of diverse hinge-binding scaffolds for selective Aurora kinase inhibitors.

Four hinge-binding scaffolds have been explored for novel selective Aurora kinase inhibitors. The structure activity relationship, selectivity and pharmacokinetic profiles have been evaluated.

Assessing renal function: Some significant improvements on the horizon.

Diaryldiamines with Dual Inhibition of the Histamine H(3) Receptor and the Norepinephrine Transporter and the Efficacy of 4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidin-1-yl)ethoxy)naphthalen-1-ol in Pain.

A series of compounds was designed as dual inhibitors of the H(3) receptor and the norepinephrine transporter. Compound 5 (rNET K(i) = 14 nM; rH(3)R K(i) = 37 nM) was found to be efficacious in a rat...