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Arginase Explains Angina In Diabetics

In a new study published in the scientific journal Circulation, scientists at Karolinska Institutet and Karolinska University Hospital show that an enzyme called arginase might have a key part to play...

Arginase might play a role in development of cardiovascular disease in type II diabetics

In a new study published in the scientific journal Circulation, scientists at Karolinska Institutet and Karolinska University Hospital in Sweden show that an enzyme called arginase might have a key pa...

Enzyme explains angina in diabetics

(Medical Xpress)—In a new study published in the scientific journal Circulation, scientists at Karolinska Institutet and Karolinska University Hospital show that an enzyme called arginase might have...

Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia

Immunohistochemical pitfalls and the importance of glypican 3 and arginase in the diagnosis of scirrhous hepatocellular carcinoma

Long-term Survival of the Juvenile Lethal Arginase-deficient Mouse With AAV Gene Therapy

Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

Biotransformation of L-ornithine from L-arginine using whole-cell recombinant arginase.

A recombinant arginase was generated for a whole-cell biotransformation system to convert L-arginine to L-ornithine in Escherichia coli. The gene ARG1 coding arginase from Bos taurus liver was synthes...

Experimental studies of OH° radical/pressure dependence of arginase activity using a molecular chromatography approach.

Arginase is an enzyme which plays a role in pathophysiology such as hypertension. Here we demonstrated for the first time the direct implication of pressure and OH° radical formation on the arginase...

Binding of α,α-Disubstituted Amino Acids to Arginase Suggests New Avenues for Inhibitor Design.

Arginase is a binuclear manganese metalloenzyme that hydrolyzes l-arginine to form l-ornithine and urea, and aberrant arginase activity is implicated in various diseases such as erectile dysfunction,...

Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells.

Increased arginase activity in the vasculature has been implicated in the regulation of nitric oxide (NO) homeostasis, leading to the development of vascular disease and the promotion of tumor cell gr...

A novel selectable marker based on Aspergillus niger arginase expression.

Selectable markers are valuable tools in transforming asexual fungi like Aspergillus niger. An arginase (agaA) expression vector and a suitable arginase-disrupted host would define a novel nutritional...