ATX-MS-1467 for patients with multiple sclerosis (MS)

ATX-MS-1467 is a novel treatment that was developed with the aim of working with the immune system to treat the underlying cause of disease rather than just treating the symptoms or suppressing the...

Interleukin 1 IL 1 Receptor IL 1R

Interleukin-1 (IL-1) beta is a proinflammatory cytokine driving joint inflammation as well as systemic signs of inflammation, such as fever and acute phase protein production. Current therapy targetin...

TNF-Kinoid

Therapies targeting TNF have already demonstrated efficacy across a wide range of inflammatory diseases, including rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondulitis, psoria...

Zelboraf dosing rework

NIBR and UCSF researchers have shown that altering the dosing regimen of Zelboraf can prevent the development of drug resistance in mouse models of melanoma. The team will now test an intermittent Zel...

Peristaltic Pumps for the Pharmaceutical Industry

Vederflex have provided an award winning pharmaceutical dosing pump for MethaMeasure, helping to deliver a new kind of methadone dosing system. The pump will automate the dosing process, making rehab...

Precise dosing in microlitre range

Burkert presents micro dosing unit for liquids

Johnson Electric introduces miniature medication dosing system technology

Johnson Electric today announced a miniature medication dosing system technology under the Johnson Medtech brand. The subsystem platform provides a high precision dosing accuracy over device operatio...

Call to adjust chemo dosing for obesity

Consistent guidance around dosing chemotherapy for obese patients is needed in the UK, members of the British Oncology Pharmacy Association...

Pain Dosing Hit or Miss for Heavy Kids (CME/CE)

(MedPage Today) -- Healthcare professionals and parents are inconsistent when it comes to acetaminophen dosing in children who weigh more than average for their age, researchers found.

RXi completes dosing in RXI-109 Phase 1 study

RXi Pharmaceuticals, a biotechnology company, has completed dosing in Phase 1 study of RXI-109, a self-delivering RNAi compound.

Colistin: Optimal Dosing and Outcomes?

Paul G. Auwaerter, MD, describes the latest thinking on the use and dosing of colistin. Medscape Infectious Diseases

A comparison of ECT dosing methods using a clinical sample.

Several methods have been used to determine ECT dose based on formulae, protocols or fixed-dosing. This study aims to explore the relative utility of these ECT dosing methods.

Development of a micro-dosing system for fine powder using a vibrating capillary. Part 2. The implementation of a process analytical technology tool in a closed-loop dosing system.

In an earlier study, a micro-dosing system for fine powder using a vibrating capillary which can precisely dose various lactose powders, was introduced. In scaling up to a multi-track dosing system, i...

Randomised clinical trial: pre-dosing with taribavirin before starting pegylated interferon vs. standard combination regimen in treatment-naïve patients with chronic hepatitis C genotype 1.

BACKGROUND: Combination therapy with the ribavirin (RBV) prodrug taribavirin (TBV) and pegylated interferon (PIFN) has produced lower rates of anaemia than with RBV and PIFN. Studies have demonstrated...

Single dose pharmacokinetics and absolute bioavailability of mirabegron, a β3-adrenoceptor agonist for treatment of overactive bladder.

Background and objectives: Mirabegron is a potent and selective β3-adrenoceptor agonist in development for treatment of overactive bladder. Methods: Mirabegron pharmacokinetics after single intraveno...

In pediatric patients, age has more impact on dosing of vitamin K antagonists than VKORC1 or CYP2C9 genotypes.

Anticoagulation with Vitamin K antagonists (VKA) is problematic due to difficulties in safely managing dosing. Polymorphisms in cytochrome P450 C9 (CYP2C9) and vitamin K epoxide reductase genes (VKORC...