Search Results for "Elevated D Dimer And Malignancy"
Original Source: Elevated D-dimers are also a marker of underlying malignancy and increased mortality in the absence of venous thromboembolism.
Background D-dimers are used in conjunction with clinical probability scores in the assessment of venous thromboembolism (VTE), and they are elevated in other conditions, including malignancy, infection and arrhythmias. High levels of D-dimers in VTE are associated with adverse outcomes, including increased mortality. Their significance in patients without VTE has not previously been established. Aims To establish the clinical significance of elevated D-dimer levels in patients without VTE. Methods This pro...
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Elevated HighDensity Lipoprotein Levels
Lymphoma is a cancer of the lymph nodes; classified as Hodgkin or non-Hodgkin lymphoma. Malignancy varies, and the prognosis can be from a few months to many years. Symptoms include enlarged lymph...
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DAXX envelops an H3.3–H4 dimer for H3.3-specific recognition
The crystal structures of the histone chaperone DAXX histone-binding domain bound to a histone H3.3–H4 dimer are described; DAXX wraps around the H3.3–H4 dimer and alters its conformation.
Dimer asymmetry defines α-catenin interactions
The protein α-catenin has an essential role in stabilizing cell-cell junctions, and it is involved in multiple interactions with other cytoskeleton proteins. The crystal structure of nearly full-leng...
Increasing the efficiency of D-dimer tests
JAMA Intern Med2013;158:93-100 Researchers from Canada have designed and tested a strategy of selective D-dimer testing for adults with suspected first deep vein thrombosis (DVT), in an attempt to......
Targeted D-dimer Testing Best for DVT Diagnosis
Basing D-dimer testing on a patient's clinical pretest probability for deep vein thrombosis can enable providers to exclude DVT in more patients without increasing missed diagnoses. Medscape Medical...
Selective strategy for D-dimer testing in DVT
Selecting certain patients for D-dimer testing appears to be a safe and more efficient way of diagnosing deep vein thrombosis than uniformly testing all patients suspected of having the condition, rep...
Selective Use of D-Dimer Test for Deep Vein Thrombosis
D-dimer testing based on clinical pretest probability for deep vein thrombosis is safe and reduces diagnostic testing compared with...
Children and young adult thyroid cancer patients who are treated with radioactive iodine have an elevated risk of developing a second primary malignancy, according to new data.
Objective To review the diagnostic accuracy of D-dimer testing in older patients (>50 years) with suspected venous thromboembolism, using conventional or age adjusted D-dimer cut-off values.Design......
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Background D-dimers are used in conjunction with clinical probability scores in the assessment of venous thromboembolism (VTE), and they are elevated in other conditions, including malignancy, infecti...
Acute Stroke Patients Have Occult Malignancy More Often than Expected.
The aim of the present study was to investigate the frequency of having occult malignancy in patients with acute ischemic stroke and their clinical characteristics. We retrospectively enrolled 1,714 c...
Glioblastoma multiforme (GBM), the most common primary tumor of the central nervous system, is associated with a state of hypercoagulability. We hypothesized that tumor activity is displayed by elevat...
D-Dimer for risk stratification in patients with acute pulmonary embolism.
Background: Risk stratification is currently recommended for the initial management of patients with acute pulmonary embolism (PE). Methods: We performed a meta-analysis of studies in patients with ac...
Evaluation of plasma d-dimer plus fibrinogen in predicting acute CVST.
BACKGROUND: Prompt diagnosis of cerebral venous sinus thrombosis is a challenge owing in part to its complex and non-specific early clinical symptoms. OBJECTIVE: This study aims to evaluate the value...
