Search Results for "Expression Of Snp Genes"
Original Source: SNP discovery, expression and cis-regulatory variation in the UGT2B genes.
UGT2B enzymes metabolize multiple endogenous and exogenous molecules, including steroid hormones and clinical drugs. However, little is known about the inter-individual variation in gene expression and its determinants. We re-sequenced candidate regulatory regions and the partial coding regions (41.1 kb) of UGT2B genes and identified 332 genetic variants. We measured gene expression in normal breast and liver samples and observed different patterns. The expression levels varied greatly across individuals...
Matching Channels
In biology, and specifically genetics, epigenetics is the study of changes in gene expression caused by mechanisms other than changes in the underlying DNA sequence – hence the name epi- (Gree...
Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful in identifying tumor cells and are potential candidates f...
At OncoDNA, our philosophy is to provide the most suitable test in terms of rapidity and cost. That’s why we follow a 3 tier approach to find tumour mutations which can respond to new cancer t...
Despite the humorous name, hedgehog signalling cascades are central to embryonic development and has been implicated in the development of a number of diseases, including cancer. The downstream ca...
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Virus particles (known as virions) consist of two or three parts: the genetic material made from eit...
Matching News
Decreased expression of synapse-related genes and loss of synapses in major depressive disorder
Ronald Duman and colleagues report that synapse number is reduced in subjects with major depressive disorder. This is associated with decreased expression of synapse-related genes and increased expres...
MicroRNA-218 especially low in medulloblastoma
Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the e...
Medulloblastoma Targeted By MicroRNA-218
Between the blueprint of the genome and the products of its expression lie microRNAs, which can boost or lower the rate at which genes become stuff. In fact, many cancers use microRNA to magnify the e...
Gene expression and peripheral blood as tools for pinpointing genes linked to autism
UCLA researchers have combined two tools - gene expression and the use of peripheral blood -- to expand scientists' arsenal of methods for pinpointing genes that play a role in autism. Published in th...
Patient Survival In Non-Hodgkins Lymphoma Predicted By Epigenomic Abnormalities
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published in the journal PLOS Genetics shows...
Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
Think of the epigenome like a giant musical mixing board, turning up or down the expression of various genes. A University of Colorado Cancer Center study published today in the journal PLOS Genetics...
Bacterial physiology: Unfit expression
In bacteria, little correlation exists between fitness and gene expression, and genes are often controlled suboptimally.
New tools for targeting genes linked to autism
Researchers have combined two tools – gene expression and the use of peripheral blood -- to expand scientists’ arsenal of methods for pinpointing genes that play a role in autism. The findings cou...
Matching PubMed Articles
Dual-Color Luciferase Mouse Directly Demonstrates Coupled Expression of Two Clock Genes.
We have established a dual-color transgenic mouse that simultaneously reports the expression of two clock genes, Bmal1 and Per2, in a single tissue. The expression of the two genes is monitored with g...
Genes that escape from X inactivation.
To achieve a balanced gene expression dosage between males (XY) and females (XX), mammals have evolved a compensatory mechanism to randomly inactivate one of the female X chromosomes. Despite this chr...
Prognostic value of tumor progression-related gene expression in colorectal cancer patients.
PURPOSE: Colorectal cancer (CRC) is driven by genetic alterations causing its progression. Besides accepted tumor suppressor- and onco- genes, a series of genes have been identified, which contribute...
Reference genes for measuring mRNA expression.
The aim of this review is to find answers to some of the questions surrounding reference genes and their reliability for quantitative experiments. Reference genes are assumed to be at a constant expre...
A comparison between different reference genes for expression studies in human hippocampal tissue.
The reliability of gene expression studies by mRNA quantification is highly dependent upon several experimental procedures, including the choice of reference genes used for data normalization. In orde...
