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Search Results for "FMNL3"

05:32 EDT 24th May 2013 | BioPortfolio

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FMNL3 FH2–actin structure gives insight into formin-mediated actin nucleation and elongation

Formins regulate actin nucleation and filament elongation through their conserved FH2 domain. The formin FMNL3 induces assembly of filopodia, and now the crystal structure of its FH2 domain in complex...

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Assembly of filopodia by the formin FRL2 (FMNL3).

Actin-dependent finger-like protrusions such as filopodia and microvilli are widespread in eukaryotes, but their assembly mechanisms are poorly understood. Filopodia assembly requires at least three b...

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