Creatinine clearance

DAXX envelops an H3.3–H4 dimer for H3.3-specific recognition

The crystal structures of the histone chaperone DAXX histone-binding domain bound to a histone H3.3–H4 dimer are described; DAXX wraps around the H3.3–H4 dimer and alters its conformation.

FDA Grants Diazyme 510(k) Clearance to Market Its D-Dimer Assay for Clinical Chemistry Analyzers

SAN DIEGO, CA -- (Marketwire) -- 02/12/13 -- Diazyme Laboratories today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) clearance to market its D-Dimer assay. In line wi...

Dimer asymmetry defines α-catenin interactions

The protein α-catenin has an essential role in stabilizing cell-cell junctions, and it is involved in multiple interactions with other cytoskeleton proteins. The crystal structure of nearly full-leng...

Increasing the efficiency of D-dimer tests

JAMA Intern Med2013;158:93-100 Researchers from Canada have designed and tested a strategy of selective D-dimer testing for adults with suspected first deep vein thrombosis (DVT), in an attempt to......

Targeted D-dimer Testing Best for DVT Diagnosis

Basing D-dimer testing on a patient's clinical pretest probability for deep vein thrombosis can enable providers to exclude DVT in more patients without increasing missed diagnoses. Medscape Medical...

Selective strategy for D-dimer testing in DVT

Selecting certain patients for D-dimer testing appears to be a safe and more efficient way of diagnosing deep vein thrombosis than uniformly testing all patients suspected of having the condition, rep...

Selective Use of D-Dimer Test for Deep Vein Thrombosis

D-dimer testing based on clinical pretest probability for deep vein thrombosis is safe and reduces diagnostic testing compared with...

Diagnostic accuracy of conventional or age adjusted D-dimer cut-off values in older patients with suspected venous thromboembolism: systematic review and meta-analysis

Objective To review the diagnostic accuracy of D-dimer testing in older patients (>50 years) with suspected venous thromboembolism, using conventional or age adjusted D-dimer cut-off values.Design......

Age and gender specific cut-off values to improve the performance of D: -dimer assays to predict the risk of venous thromboembolism recurrence.

The Prolong study shows that continuing vitamin K antagonists (VKA) in patients with abnormal D: -dimer (evaluated by a qualitative assay, Clearview Simplify D: -dimer) results in a significant reduct...

Analytical and clinical validation of a new point-of-care testing system for determination of D-Dimer in human blood.

D-Dimer testing is used for exclusion of deep venous thrombosis (DVT). AQT90 FLEX D-Dimer (AQT D-Dimer) is a novel time-resolved fluorescence based point-of-care test for quantification of D-Dimer in...

Surface-assisted transfer hydrogenation catalysis on a γ-Al(2)O(3)-supported Ir dimer.

A novel oxide-supported Ir dimer, which was found to be active for transfer hydrogenation of aromatic ketones, was prepared on a γ-Al(2)O(3) surface from an Ir dimer complex [Ir(2){η(5)-C(5)(CH(3))(...

Does fluoromethane form a hydrogen bond with water?

Fluorinated organic compounds have become increasingly important in the pharmaceutical and agricultural industries. However, even the simplest aspects of these compounds are still not well understood....

Effects of ramp negotiation, paving type and shoe sole geometry on toe clearance in young adults.

Trips are a major cause of falls and result from involuntary contact of the foot with the ground during the swing phase of gait. Adequate toe clearance during swing is therefore crucial for safe locom...