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ART for HIV May Protect Against HBV

In a study of men with HIV, antiretroviral therapy (ART) with lamivudine or tenofovir disoproxil fumarate (TDF) appeared to protect against infection with hepatitis B virus (HBV). Reuters Health Inf...

Switch From Epzicom to Truvada Maintains HIV Suppression: Study

Virologic suppression was maintained when HIV patients switched from lamivudine/abacavir (ABC/3TC) to emtricitibine/tenofovir (FTC/TDF) in the pharma-funded SWIFT study. Reuters Health Information

Human medicines European Public Assessment Report (EPAR): Lamivudine Teva, lamivudine, Revision: 1, Authorised

Human medicines European Public Assessment Report (EPAR): Lamivudine Teva Pharma B.V., lamivudine, Revision: 1, Authorised

Top Takeaway From ICAAC 2012: More Good News on Dolutegravir

Dr. Paul Sax reviews data from the SINGLE trial presented at ICAAC 2012 on the benefits of dolutegravir/abacavir/lamivudine vs tenofovir/emtricitabine/efavirenz. Medscape HIV/AIDS

Human medicines European Public Assessment Report (EPAR): Lamivudine/Zidovudine Teva, lamivudine / zidovudine, Revision: 1, Authorised

Human medicines European Public Assessment Report (EPAR): Lamivudine/Zidovudine Teva, lamivudine / zidovudine, Revision: 2, Authorised

Tenofovir DF safe and effective in treating adolescents with HBV

A recent clinical trial found that the adult antiviral drug, tenofovir disoproxil fumarate (tenofovir DF), is safe and effective in treating adolescents with hepatitis B virus (HBV). Trial results pub...

Comparison of changes in bone density and turnover with abacavir-lamivudine versus tenofovir-emtricitabine in HIV-infected adults: 48-week results from the ASSERT study.

BACKGROUND: Abacavir-lamivudine and tenofovir DF-emtricitabine fixed-dose combinations are commonly used as first-line antiretroviral therapies. However, few studies have comprehensively compared thei...

Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantation with entecavir plus tenofovir combination therapy and perioperative hepatitis B immunoglobulin only.

T. Karlas, J. Hartmann, A. Weimann, M. Maier, M. Bartels, S. Jonas, J. Mössner, T. Berg, H.L. Tillmann, J. Wiegand. Prevention of lamivudine-resistant hepatitis B recurrence after liver transplantati...

Low level of the K103N HIV-1 above a threshold is associated with virological failure in treatment-naive individuals undergoing efavirenz-containing therapy.

: Study GS-01-934 was a randomized open-label phase III study comparing efavirenz and tenofovir/emtricitabine to efavirenz and zidovudine/lamivudine in treatment-naive HIV-1-infected individuals. Thro...

Tenofovir-associated proteinuria.

Proteinuria was observed in 27% of 153 patients taking tenofovir for more than 1 year. Concomitant protease inhibitor therapy and cumulative tenofovir exposure were independently associated with prote...

Tenofovir Monotherapy and Tenofovir Plus Entecavir Combination as Rescue Therapy for Entecavir Partial Responders.

BACKGROUND AND AIMS: Despite high potency, a significant proportion of patients treated with entecavir achieve only partial viral suppression. Our goal was to examine the complete viral suppression ra...