The Top 100 Drugs

The pharmaceutical industry is massive, both in range of products and in financial values. These are the top 200 drugs (ranked in descending order according to total sales in 20010, $), and the co...

Generic Tricor could boost Lupin in the US but shadow on Antara

Lupin has introduced fenofibrate tablets 48mg and 145mg, generic versions of Abbott's TriCor, on the US market, in what’s seen as a ‘material’ launch for the Indian firm in the short...

Whistleblower: Abbott off-label TriCor scheme put patients at risk

Abbott "trained, directed, incentivized and encouraged" its sales representatives to market TriCor (fenofibrate) for unapproved uses and to "misrepresent and withhold clinical information" about the...

Mylan Launches Generic Tricor Tablets

PITTSBURGH, May 17, 2013 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that its subsidiary Mylan Pharmaceuticals Inc. has shipped Fenofibrate Tablets, 48 mg and 145 mg. Mylan Pharmaceut...

Lupin Launches Generic TRICOR® Tablets

MUMBAI, India and BALTIMORE, November 20, 2012 /PRNewswire/ -- Pharma major, Lupin Ltd., announced today that its subsidiary, Lupin Pharmaceuticals Inc. (collectively, Lupin) has launched its Fenofib...

Mylan Launches Generic Tricor® Tablets

PITTSBURGH, May 17, 2013 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that its subsidiary Mylan Pharmaceuticals Inc. has shipped Fenofibrate Tablets, 48 mg and 145 mg. Mylan Pharmaceutical...

India's Lupin launches generic TriCor in U.S.

MUMBAI, Nov 20 (Reuters) - Indian drugmaker Lupin Ltd said on Tuesday it launched a generic version of Abbott Laboratories' cholesterol lowering drug TriCor in the United States.

More downs than ups for Ranbaxy

A further problem with Indian generics manufacturer Ranbaxy Laboratories (Ranbaxy) could affect its reputation yet again with US FDA. This time, Ranbaxy fell foul of an Indian state regulator, the Mah...

Statins and fenofibrate safe in mixed dyslipidemia

NEW YORK (Reuters Health) - Adding fenofibrate to statin therapy doesn't appear to have ill effects in patients with combined hyperlipidemia, Chinese researchers say.

Synthesis of highly water-soluble fibrate derivatives via BGLation.

Three water-soluble fibrates (fenofibrate, bezafibrate and chlofibrate) conjugated with a symmetrically branched glyceryl trimer (BGL003) were synthesized, and an evaluation of the fenofibrate-BGL003...

Fenofibrate promotes ischemia-induced revascularization through adiponectin-dependent pathway.

Recent clinical trials demonstrated that PPARalpha agonist fenofibrate reduces cardiovascular events including limb amputation in people with type 2 diabetes. Here we investigated whether fenofibrate...

Fenofibrate ameliorates cardiac hypertrophy by activation of peroxisome proliferator-activated receptor-α partly via preventing p65-NFκB binding to NFATc4.

Fenofibrate, a specific peroxisome proliferator-activated receptor alpha (PPAR-α) agonist, was reported to inhibit cardiac hypertrophy. However, the detailed molecular mechanisms and particularly the...

Combination of Fenofibrate with Non-Statin Drug Regimens.

Objective: We present the available data on the effects of combined therapy of fenofibrate with drugs affecting lipid metabolism other than statins. Methods: We consider studies evaluating the effects...

ApoB genetic variants modify the response to fenofibrate: a GOLDN study.

Hypertriglyceridemia, defined as a triglyceride measurement > 150 mg/dl, occurs in up to 34% of adults. Fenofibrate is a commonly used drug to treat hypertriglyceridemia, but response to fenofibrate v...