Search Results for "Fetuin A Tlr4 Nature Medicine July 2012"
Original Source: Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
Excess free fatty acids (FFAs) are known to induce insulin resistance, and a role for TLR4 has been implicated in this process. But FFAs are believed to be incapable of binding TLR4 directly. In a new study, Samir Bhattacharya and colleagues show tha...
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Traditional Chinese Medicine (simplified Chinese: 中医; traditional Chinese: 中醫; pinyin: zhōng yī: "Chinese Medicine") refers to a broad range of medicine practices sharing common...
Tropical Medicine is the study of diseases more commonly found in tropical regions than elsewhere. Examples of these diseases are malaria, yellow fever, Chagas disease, Dengue, Helminths, African tr...
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Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance
Excess free fatty acids (FFAs) are known to induce insulin resistance, and a role for TLR4 has been implicated in this process. But FFAs are believed to be incapable of binding TLR4 directly. In a new...
Signalling: PI3Kδ keeps TLR4 signalling on track
PI3Kδ regulates TLR4 signalling by controlling the subcellular localization of TLR4 and TIRAP.
Scientists uncover new role for TLR4 in development of tissue fibrosis or scarring
An international multi-disciplinary research team led by Northwestern Medicine scientists has uncovered a new role for the protein toll-like receptor 4 (TLR4) in the development of tissue fibrosis, or...
Fetuin-A levels linked to cardiovascular disease risk
(HealthDay)—In elderly individuals without type 2 diabetes, high levels of fetuin-A, a protein that inhibits arterial calcification and insulin action, is associated with a lower risk of cardiovascu...
Pathway Discovered That Has Potential Implications For Scleroderma Therapy
An international multi-disciplinary research team led by Northwestern Medicine scientists has uncovered a new role for the protein toll-like receptor 4 (TLR4) in the development of tissue fibrosis, or...
Premature Hardening Of The Zona Pellucida Can Be A Cause Of Infertility
Scientists in Mainz and Aachen have discovered a new mechanism that controls egg cell fertility and that might have future therapeutic potential. It was revealed by Professor Dr. Walter Stocker of the...
The TLR4 antagonist Eritoran protects mice from lethal influenza infection
There is a pressing need to develop alternatives to annual influenza vaccines and antiviral agents licensed for mitigating influenza infection. Previous studies reported that acute lung injury caused...
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BACKGROUND:: Fetuin A, a predictor of mortality in dialysis patients, is associated with vascular calcification and atherosclerosis in hemodialysis (HD) patients. Whether it predicts arteriovenous (AV...
Fetuin-A and Cystatin C Are Endogenous Inhibitors of Human Meprin Metalloproteases.
Meprin α and β, zinc metalloproteinases, play significant roles in inflammation, including inflammatory bowel disease (IBD), possibly by activating cytokines, like interleukin 1β, interleukin 18, o...
Clinical studies and animal experiments have shown that the serum protein fetuin-A is a highly effective inhibitor of soft tissue calcification. This inhibition mechanism was elucidated on the basis...
ABSTRACT: BACKGROUND: Ambigous results exist on fetuin-A as marker for vascular disease in type 2 diabetes. This study aims to define the role of fetuin-A as marker for micro- and macrovascular diseas...
The identity of the cell adhesive factors in fetal bovine serum, commonly used to supplement growth media, remains a mystery due to the plethora of serum proteins. In the present analyses, we showed t...
