Search Results for "Fingolimod Hplc Method"

01:26 EDT 4th August 2015 | BioPortfolio

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DNA-FISH Probes

Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid...

Spirometry Test

The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...

Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...

Breast Implants - Augmentation

Breast implants are medical devices that are used to augment breast size or to reconstruct the breast following mastectomy or to correct a congenital abnormality. Breast implants consist of a silico...

ImuXen

ImuXen® is a liposomal technology platform designed to improve the delivery and effectiveness of DNA, protein and polysaccharide vaccines. Proof of concept preclinical studies with a number of...

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Cleaning Validation Method Using Swab Technique

A cleaning validation method has been developed for MICRO 90 Concentrated Cleaning Solution using a swab recovery technique and quantification with HPLC with charged aerosol detection (CAD) and mass s...

NEW ACE Method Development Kits for UHPLC / HPLC

ACE columns offer chromatographers an extremely powerful and reliable approach to UHPLC and HPLC method development. Based upon an ultra-inert, high efficiency silica, ACE phases incorporate the lates...

New applications of drug fingolimod to improve cognitive deficits in Huntington's disease

Fingolimod, a drug used to treat multiple sclerosis, restores hippocampal synaptic plasticity and improves memory function. This is the main conclusion of a study in a mouse model of Huntington diseas...

HPLC Column Addresses Difficult-to-Resolve Compounds

Phenomenex introduces the Kinetex C8 5-micron core-shell HPLC column. The used C8 phase delivers retention for the analysis of hydrophobic and “sticky” compounds. In combination with Kinetex Core-...

Fingolimod in relapsing remitting multiple sclerosis: Indication of added benefit in certain patients

Based on new analyses conducted by the drug manufacturer, an advantage can be determined in two instead of only one patient group for the use of Fingolimod in relapsing remitting multiple sclerosis. T...

Routine Generation of Powder Samples from HPLC Fractions

Genevac reports that its HT Series II Evaporator using the Fast Lyophilisation, or LyoSpeed process is enabling a growing number of pharmaceutical labs to routinely dry HPLC fraction samples to a powd...

Chilling/Heating HPLC Column Temperature Controller

Torrey Pines Scientific, Inc. announces its new EchoTherm Model CO50 Programmable HPLC Column Chiller/Heater. The unit has a temperature range from 4.0°C to 100.0°C readable and settable to 0.1°C. ...

Fingolimod in RRMS: Indication of added benefit in certain patients

Pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG), the German Institute for Quality and Efficiency in Health Care (IQWiG) reassessed fingolimod (trade name: Gilenya), a dr...

Matching PubMed Articles

Effects of Three Months Fingolimod Therapy on Heart Rate.

Fingolimod is a novel disease-modifying drug for relapsing-remitting multiple sclerosis (RRMS). Fingolimod initiation associates with a decrease in heart rate (HR). However, the long-term effects of f...

Fingolimod alters inflammatory mediators and vascular permeability in intracerebral hemorrhage.

Intracerebral hemorrhage (ICH) leads to high rates of death and disability. The pronounced inflammatory reactions that rapidly follow ICH contribute to disease progression. Our recent clinical trial d...

Initial lymphocyte count and low BMI may affect fingolimod-induced lymphopenia.

To assess whether pretreatment-lymphocyte counts, treatment before fingolimod, age, sex, or body mass index (BMI) affects the risk of fingolimod-induced lymphopenia in patients with relapsing-remittin...

Second-Line Therapy with Fingolimod for Relapsing-Remitting Multiple Sclerosis in Clinical Practice: The Effect of Previous Exposure to Natalizumab.

Background: To evaluate efficacy and safety of fingolimod for relapsing-remitting multiple sclerosis, particularly in patients previously exposed to natalizumab. Method: Prospective observational sing...

Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis.

Effect of fingolimod in multiple sclerosis (MS) is thought to involve the prevention of lymphocyte egress from lymphoid tissues, thereby reducing autoaggressive lymphocyte infiltration into the centra...

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