Search Results for "Fingolimod Hplc Method"

08:23 EDT 4th September 2015 | BioPortfolio

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DNA-FISH Probes

Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid...

Spirometry Test

The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...

Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...

Breast Implants - Augmentation

Breast implants are medical devices that are used to augment breast size or to reconstruct the breast following mastectomy or to correct a congenital abnormality. Breast implants consist of a silico...

ImuXen

ImuXen® is a liposomal technology platform designed to improve the delivery and effectiveness of DNA, protein and polysaccharide vaccines. Proof of concept preclinical studies with a number of...

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Cleaning Validation Method Using Swab Technique

A cleaning validation method has been developed for MICRO 90 Concentrated Cleaning Solution using a swab recovery technique and quantification with HPLC with charged aerosol detection (CAD) and mass s...

NEW ACE Method Development Kits for UHPLC / HPLC

ACE columns offer chromatographers an extremely powerful and reliable approach to UHPLC and HPLC method development. Based upon an ultra-inert, high efficiency silica, ACE phases incorporate the lates...

Intelligent Solutions for UHPLC / HPLC Method Development – ACE Method Development Kits

ACE Method Development Kits are designed to maximise selectivity – the key to resolution in chromatography.  A complete range of kits for all requirements is available, including kits feat...

Third Case of PML With Fingolimod (Gilenya) in MS

Novartis reports a third case of progressive multifocal leukoencephalopathy in a patient with relapsing multiple sclerosis treated with fingolimod. News Alerts

FDA issues new PML warning for fingolimod

The US Food and Drug Administration has issued a new safety warning about cases of a rare brain infection in multiple sclerosis patients taking fingolimod (Gilenya).

Switching From Natalizumab to Fingolimod in RRMS

This study aims to improve our understanding of drug-induced immune changes and potential disease exacerbation during switch-over from natalizumab to fingolimod in treatment of RRMS. BMC Neurology

HPLC Column Addresses Difficult-to-Resolve Compounds

Phenomenex introduces the Kinetex C8 5-micron core-shell HPLC column. The used C8 phase delivers retention for the analysis of hydrophobic and “sticky” compounds. In combination with Kinetex Core-...

New applications of drug fingolimod to improve cognitive deficits in Huntington's disease

Fingolimod, a drug used to treat multiple sclerosis, restores hippocampal synaptic plasticity and improves memory function. This is the main conclusion of a study in a mouse model of Huntington diseas...

Matching PubMed Articles

Effects of Three Months Fingolimod Therapy on Heart Rate.

Fingolimod is a novel disease-modifying drug for relapsing-remitting multiple sclerosis (RRMS). Fingolimod initiation associates with a decrease in heart rate (HR). However, the long-term effects of f...

Fingolimod alters inflammatory mediators and vascular permeability in intracerebral hemorrhage.

Intracerebral hemorrhage (ICH) leads to high rates of death and disability. The pronounced inflammatory reactions that rapidly follow ICH contribute to disease progression. Our recent clinical trial d...

Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis.

Effect of fingolimod in multiple sclerosis (MS) is thought to involve the prevention of lymphocyte egress from lymphoid tissues, thereby reducing autoaggressive lymphocyte infiltration into the centra...

Comparison of the QMS® analyzer with HPLC-UV for the quantification of lamotrigine concentrations in human plasma samples.

Recently, a turbidimetric immunoassay method has been developed for use in the form of a QMS lamotrigine (LTG) commercial immunoassay. The present study was designed to evaluate the performance of thi...

Simultaneous determination of synthetic colorants in yogurt by HPLC.

This article reports on a method to determine synthetic dyes in yogurts and milk drinks. Initially a method for extraction of artificial dyes was developed to pretreat samples in order to extract most...

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