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Search Results for "Fingolimod Hplc Method"

20:33 EDT 26th June 2016 | BioPortfolio

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DNA-FISH Probes

Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid...

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New EMA Advice for PML Prevention With Fingolimod in MS

The European Medicines Agency recommends evaluating patients for progressive multifocal leukoencephalopathy and for basal cell carcinoma before and during treatment with fingolimod (Gilenya). News A...

#jobs #lifescience Cranleigh Scientific: Analytical Chemist-Formulation-HPLC-GMP-Oxford- £25k-£29k+Bonus

// GBP25000.00 – GBP29000.00 per annum + Bonus + Benefits: Cranleigh Scientific: Analytical Chemist-Formulation-HPLC-GMP-Oxford- £25k-£29k+Bonus-Method Development-Inhaled Products A specialit...

S1P1R variation may cause differential patient responses to fingolimod treatment

Multiple sclerosis (MS) is an autoimmune disorder that results in demyelination of neurons. The FDA-approved drug fingolimod (Gilenya, FTY-720) modulates signaling by the bioactive lipid sphingosine-1...

Long-term Treatment With Fingolimod in MS

The results of this study support a continued beneficial effect of long-term fingolimod therapy in patients with relapsing-remitting multiple sclerosis. Journal of Neurology, Neurosurgery, and Psych...

Fingolimod Easier to Swallow Than Dimethyl Fumarate?

Patients with multiple sclerosis are more likely to discontinue dimethyl fumarate than fingolimod after 2 years or less, largely because of tolerability issues, a real-world study has found. Medsca...

Receptor variation influences fingolimod efficacy in mouse multiple sclerosis models

(JCI Journals) In this issue of JCI Insight, May Han of Stanford University and colleagues tested the hypothesis that genetic variants of the cell surface receptor that responds to S1P, S1PR1, may inf...

Rituximab outperforms fingolimod after natalizumab switch

Rituximab is more effective and better tolerated than fingolimod for patients with multiple sclerosis needing to switch from natalizumab due to JC-virus antibody positivity, research suggests.

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discont...

Matching PubMed Articles

Effect of fingolimod on cardiac autonomic regulation in patients with multiple sclerosis.

Fingolimod modulates sphingosine-1-phosphate receptors that are also found in cardiovascular tissue.

Development of a HPLC Method for the Quantitative Determination of Capsaicin in Collagen Sponge.

Controlling the concentration of drugs in pharmaceutical products is essential to patient's safety. In this study, a simple and sensitive HPLC method is developed to quantitatively analyze capsaicin i...

Qualitative and quantitative analysis of chemical constituents of Centipeda minima by HPLC-QTOF-MS & HPLC-DAD.

A high performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (HPLC-QTOF-MS) method in both positive and negative ion modes was established to investigate the major...

Performance review of a fast HPLC-UV method for the quantification of chlorogenic acids in green coffee bean extracts.

The aim of this study was to test the performance of a HPLC method, designated for rapid quantification of chlorogenic acids (CGA) in green coffee extract (GCE). The precision statistics associated wi...

Kaposi sarcoma in a fingolimod-treated patient with multiple sclerosis.

Kaposi sarcoma (KS) is a vascular tumour of endothelial cell origin, associated with human herpes virus 8. It develops in one of four clinical settings, one of which is iatrogenic immunosuppression. W...

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