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Transplantation: Optimizing outcomes in elderly kidney transplant recipients

New data suggest that the survival of elderly kidney transplant recipients is better than that of the general elderly population. These findings draw attention to the growing category of elderly patie...

Transplant Promising as MS Therapy (CME/CE)

ORLANDO (MedPage Today) -- High-dose immunosuppressant therapy and autologous hematopoietic stem cell transplant induced durable freedom from relapses and MRI lesions in patients with multiple scleros...

Renal Function After Conversion From a Calcineurin Inhibitor

Conversion from cyclosporine to everolimus improves one-year renal function post kidney transplant, but what is the trade-off? American Journal of Transplantation

University of Cincinnati leads first trial on steroid and CNI withdrawal post-transplant

(University of Cincinnati Academic Health Center) The University of Cincinnati will lead a $5.2 million national trial studying removal of both corticosteroids and common immunosuppression treatments...

Novartis new two-year data with Certican shows positive outcomes at 24 months in largest liver ...

Study's endpoints met; Certican with reduced exposure tacrolimus provided comparable efficacy with superior renal function maintained from month one to 24 versus control arm [1] Calcineurin i...

ARB No Help in Saving Kidney Grafts (CME/CE)

(MedPage Today) -- Treatment with an angiotensin receptor blocker did not slow progression of end-stage renal disease or its precursor in kidney transplant recipients, a randomized trial showed.

AbbVie begins atrasentan Phase 3 diabetic nephropathy study

AbbVie has begun Phase 3 study of atrasentan on renal outcomes including the onset of end-stage renal disease (ESRD) transplant or death due to renal failure progression in patients with diabetic neph...

Cotinine Levels Predict Poor Outcome After Renal Transplant

Plasma and urinary cotinine measures predicted mortality and graft failure in renal transplant recipients in a dose-dependent fashion, and could serve as alternatives to self-reported smoking. Medsc...

Early steroid withdrawal in pediatric renal transplant: five years of follow-up.

This prospective, comparative trial investigated the impact on mean change in height standard deviation score (SDS), acute rejection rate, and renal function of early steroid withdrawal in 96 recipien...

Risk analysis for deterioration of renal function after pancreas alone transplant.

Chatzizacharias NA, Vaidya A, Sinha S, Sharples E, Smith R, Jones G, Brockmann J, Friend PJ. Risk analysis for deterioration of renal function after pancreas alone transplant. Clin Transplant 2011 DOI...

A novel mouse renal transplant technique.

Unusual presentations of BK virus infections in pediatric renal transplant recipients.

BKV has emerged as a significant pathogen in the field of transplantation, predominantly causing BKV nephropathy in renal transplant recipients and hemorrhagic cystitis in HSCT recipients. However, ca...

Tuberculosis in Renal Transplant Recipients: The Evidence for Prophylaxis.

BACKGROUND.: Tuberculosis (TB) remains a leading cause of death in endemic countries and is 20 to 70 times more common in renal transplant recipients, where it contributes to both increased morbidity...