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Search Results for "Glycopolymers Dc Sign"

00:58 EDT 20th May 2013 | BioPortfolio

Original Source: High-affinity glycopolymer binding to human DC-SIGN and disruption of DC-SIGN interactions with HIV envelope glycoprotein.

Noncovalent interactions between complex carbohydrates and proteins drive many fundamental processes within biological systems, including human immunity. In this report we aimed to investigate the potential of mannose-containing glycopolymers to interact with human DC-SIGN and the ability of these glycopolymers to inhibit the interactions between DC-SIGN and the HIV envelope glycoprotein gp120. We used a library of glycopolymers that are prepared via combination of copper-mediated living radical polymerizat...

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Sequence-Controlled Multi-Block Glycopolymers to Inhibit DC-SIGN-gp120 Binding.

Chain of command: Multi-block glycopolymers made of mannose (M, see figure), glucose, and di(ethylene glycol) ethyl ether (D) monomers were synthesized using a technique to control the polymer sequenc...

High-affinity glycopolymer binding to human DC-SIGN and disruption of DC-SIGN interactions with HIV envelope glycoprotein.

Noncovalent interactions between complex carbohydrates and proteins drive many fundamental processes within biological systems, including human immunity. In this report we aimed to investigate the pot...

Synthesis of glycopolymers by controlled radical polymerization techniques and their applications.

Natural saccharides are involved in numerous biological processes. It has been shown that these carbohydrates play a role in cell adhesion and proliferation, as well as protein stabilization, organiza...

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