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New treatment for castration-resistant prostate cancer (CRPC) patients with bone metastases. Xofigo shown in a pivotal phase III trial to significantly improve overall survival. Xofigo® with...
The next generation of p38 mitogen-activated protein kinase (MAPK) inhibitors has reached clinical proof-of-concept studies in phase II in a broad range of indications. While the previous generation o...
There has been an ongoing battle between veterans and the VA over insurance coverage related to diseases veterans say are caused by their exposure to Agent Orange in Vietnam. The VA has been reluctant...
Find out how antithyroid medications impact neutrophil counts in patients with Graves disease. Clinical Endocrinology
A veteran with a rare type of cancer may have developed the condition after being exposed to Agent Orange during the Vietnam War, reveal doctors writing in the journal BMJ Case Reports.
In this review, the advantages and disadvantages of available treatment options for young patients with Graves disease are discussed. Clinical Endocrinology
How do children who received treatment for Graves disease fare over the long term? Clinical Endocrinology
Drug discovery and development company Apitope has enrolled the first patient in the Phase I clinical trial of its peptide therapy, ATX-GD-59, to treat Graves’ disease.
Alvin Young's nickname is Dr. Orange and he thinks veterans who complain about sickness that they think is related to a toxic herbicide used in the Vietnam War are simply “freeloaders,” making up ...
Should Trump's being orange matter in the Presidential election? Is there any evidence suggesting that orange people should be treated differently from non-orange people?
Graves' disease, an autoimmune disease with heterogeneous symptoms including Graves' orbitopathy, has a combined genetic/environmental background, where variations within CD28/CTLA-4/ICOS genes are co...
Graves' disease is the most common cause of hyperthyroidism in iodine-replete areas. Although progress has been made in our understanding of the pathogenesis of the disease, no treatment targeting pat...
Treatment options for Graves' disease (GD), namely anti-thyroid drugs (ATD), surgery or radioiodine (RAI), have not changed over the past two decades. There is no 'gold-standard' treatment for GD.
Thyrotropin Receptor Antibody (TRAb)-IgM Levels Are Markedly Higher Than TRAb-IgG Levels in Graves' Disease Patients and Controls, and TRAb-IgM Production Is Related to Epstein-Barr Virus Reactivation.
Graves' disease is an autoimmune thyroid disorder that mainly presents as hyperthyroidism and is caused by thyrotropin receptor antibodies (TRAbs) that stimulate thyroid-stimulating hormone receptors....
Graves' disease (GD) is an important and prevalent thyroid autoimmune disorder. Standard therapy for GD consists of antithyroid drugs (ATD) with treatment periods of around 12 months but relapse is f...