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New Medical Tool Could Help Surgeons Carrying Out Complex Procedures In The Operating Theatre

Researchers have developed a dye which provides a quick and accurate method of checking heparin levels in the blood. Heparin is an important anti-coagulant which has a significant role in major surger...

USP Announces Change in Labeling Requirement for Total Strength of Heparin to Help Minimize Medication Errors

To address safety concerns about the expression of drug strength on labels for heparin sodium injections and heparin lock flush solutions, the U.S. Pharmacopeial Convention (USP) has revised its curre...

Protamine–heparin complex antibodies raise concerns

Almost a third of patients treated with protamine for heparin reversal during cardiopulmonary bypass develop antibodies to circulating protamine–heparin complexes, study findings suggest.

Five Years Later, Legacy Biologics Still Face ‘Next Heparin’ Risks

Several factors continue to slow efforts to modernize legacy biologics’ compendial monographs against fake ingredients like the ones someone put in heparin in 2008. Hyaluronate, the ‘poster childâ...

[Review] Heparin-induced skin lesions

Heparins are widely used for prophylaxis and treatment of thromboembolic diseases. Besides bleeding complications, heparin-induced skin lesions are the most frequent unwanted adverse effects of subcut...

[Comment] Anticoagulant therapy in acute brain ischaemia

Thrombosis plays an important part in acute ischaemic stroke, and antithrombotic therapies are a logical approach to treatment. Heparin has been advocated for acute stroke since the 1950s, and by the...

Heparin and Implantation: Any Aid for ART?

This viewpoint covers a study that examines the benefits of heparin on implantation failure after in vitro fertilization. Medscape Ob/Gyn

Thrombocytopenia common with heparin prophylaxis

NEW YORK (Reuters Health) - Thrombocytopenia is common with routine heparin prophylaxis of venous thromboembolism, researchers warn.

Heparin mapping using heparin lyases and the generation of a novel low molecular weight heparin.

Seven pharmaceutical heparins were investigated by oligosaccharide mapping by digestion with heparin lyase 1, 2, or 3, followed by high performance liquid chromatography analysis. The structure of one...

Fluorescent reporters of thrombin, heparin cofactor II, and heparin binding in a ternary complex.

Thrombin inactivation by heparin cofactor II (HCII) is accelerated by ternary complex formation with heparin. The novel active-site-labeled thrombins, [4'F]FPR-T and [6F]FFR-T, and the exosite I probe...

The association between acculturation and recreational computer use among Latino adolescents in California.

BACKGROUND: Physical inactivity like recreational computer use is a likely factor in the rising obesity prevalence among Latino adolescents. OBJECTIVES: Using the data from California Health Interview...

Analysis and characterization of heparin impurities.

This review discusses recent developments in analytical methods available for the sensitive separation, detection and structural characterization of heparin contaminants. The adulteration of raw hepar...

ICD-10 coding: poor identification of recreational drug presentations to a large emergency department.

Background Hospital episode statistics (HES) and other health service utilisation data are based upon International Classification of Disease version 10 (ICD-10) diagnostic clinical codes used in rela...