Search Results for "High Dose Busulfan Fludarabine Atg"
Original Source: Busulfan, Fludarabine, Antithymocyte Globulin (ATG) & Cyclophosphamide Conditioning Bone Marrow Transplant (BMT) for Patients With Sickle Cell Disease (SCD)
Some of the drugs used in the conditioning treatment injure blood vessels. This damage may be responsible for transplant-related neurological problems seen in patients with sickle cell disease. The reason that patients with sickle cell disease are more prone to the effects of the conditioning treatment drugs may be that many of them have pre-existing damage to the blood vessels that supply their brains. The primary goal of this study is to develop a conditioning treatment that...
Matching Channels
Prostate cancer is the most common cancer in men in the UK; affecting 250,000 men. Risk factors for prostate cancer include age (average age at diagnosis is 70), a family history and a Caribbean or...
Thimerosal is a mercury-based preservative that has been used for decades in the United States in multi-dose vials (vials containing more than one dose) of some vaccines to prevent the growth of ger...
Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...
Matching News
Fludarabine can't replace cyclophosphamide with busulfan myeloablative conditioning
NEW YORK (Reuters Health) - In patients with leukemia and myelodysplastic syndrome who need myeloablative conditioning before allogeneic hematopoietic cell transplantation (HCT), the less toxic...
In Waldenstrm macroglobulinemia, fludarabine yields better survival than chlorambucil
NEW YORK (Reuters Health) - Fludarabine improves survival compared with chlorambucil in patients with Waldenstrm macroglobulinemia (WM) and related disorders, according to the multicenter WM1 stud...
Standard-Dose vs High-Dose Multivitamin Supplements for HIV
To the Editor: In the study by Dr Isanaka and colleagues, patients with human immunodeficiency virus (HIV) receiving highly active antiretroviral therapy were treated either with standard-dose or high...
Matching PubMed Articles
Personalizing intravenous (IV) busulfan doses in children using therapeutic drug monitoring (TDM) is an integral component of hematopoietic cell transplant. The authors sought to characterize initial...
High-dose Busulfan in combination chemotherapy has been used commonly for hematopoietic stem cell transplantation. It crosses the blood-brain barrier and could cause seizure. Benzodiazepines have been...
The assessment of a hematopoietic stem cell transplant (HSCT)-specific comorbidity index (HCT-CI) has been developed to predict the risk of TRM in patients undergoing allogeneic HSCT. As the myeloabla...
BACKGROUND AND PURPOSE: Fludarabine is an adenine nucleoside analogue that has significant activity in hematological malignancies and has shown promising activity in combination with radiation in prec...
We conducted a phase I trial to determine the maximum tolerated dose (MTD) of clofarabine with high-dose busulfan followed by allogeneic stem cell transplantation (SCT) in patients with high-risk and...
