Search Results for "History Clivus Chordoma"
Original Source: Cavernous Sinus Thrombosis
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Vascular Dementia accounts for 25% of all dementias (the second most commen cause after Alzheimers. It is the cumulative effects of many small strokes - patients often have evidence of vascular path...
Xanthelasma (or xanthelasma palpebrarum) is a sharply demarcated yellowish collection of cholesterol underneath the skin, usually on or around the eyelids. Although not harmful or painful, these min...
Ovarian cancer is cancer that starts in the female reproductive organs, the ovaries. It is the fifth most common cancer among women. Women at risk of Ovarian cancer are those who have had fe...
Depression is a serious mental health condition, where sad feelings carry on for weeks or months and interfere with your life. The symptoms include feeling unhappy most of the time (but may feel a...
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Combination Chemotherapeutics for the Treatment of Chordoma
Utilizing high-throughput screening methodology, NIH scientists have identified two classes of clinically-available drugs, proteasome inhibitors and topoisomerase inhibitors, that synergize to promote...
Common Genetic Variant Strongly Linked to Rare Bone Cancer
Collaborative research funded by the Chordoma Foundation yields major discovery that could open door to new therapies DURHAM, N.C., Oct. 16, 2012 /PRNewswire-USNewswire/ -- A genetic variati...
Brachyury variation may increase risk of chordoma
A genetic variation possessed by 40% of the population is associated with a five-fold increase in risk for developing chordoma, a cancer that strikes the bones of the skull and spine.
A common single-nucleotide variant in T is strongly associated with chordoma
Adrienne Flanagan and colleagues identify a common variant in the T gene associated with strong risk of chordoma, a rare malignant bone tumor. The risk variant alters an amino acid in the DNA-binding...
- Emily Eggleston - History, Science and the History of Science [More]
This month’s exploration into a pharmaceutical company’s history is the turn of French company Sanofi, which began over 100 years ago as a number of small companies. Sanofi is one of the largest...
Bringing natural history collections out of the dark
(Pensoft Publishers) In a special issue of ZooKeys, initiated by the Natural History Museum London, Vince Smith and Vladimir Blagoderov bring together 18 papers by 81 authors to look at progress and p...
October has been our focus month on personalised medicine, so who better to delve into the history of than Roche – who has made tailoring treatments to small patient populations its core mission. I...
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A 14 year old boy presents with a gunshot wound into the roof of his mouth to lodge into the clivus, and miraciously he is neurologically intact. Keywords: gunshot wound, clivus, traumatic brain injur...
The Clivus : Anatomy, Normal Variants and Imaging Pathology.
The clivus is one of the most central parts of the skull base. As diseases of the clivus evade clinical evaluation imaging plays a pivotal role in establishing a diagnosis. This article combines the d...
Paraspinal chordoma mimicking a neurofibroma: a rare but important radiological pitfall.
We present an unusual case of a chordoma presenting as an extradural spinal tumour with extension through an expanded intervertebral foramen to form a large paraspinal mass. The magnetic resonance ima...
The biological basis for modern treatment of chordoma.
Chordomas are rare malignant tumors arising in bone of the spheno-occiput, sacrum, and vertebral column which can cause neurological deficit. Current management of chordoma involves safe resection fol...
Increasing numbers of studies support the hypothesis that chordoma arises from notochordal cell rests, although the mechanism awaits further research. Brachyury is the first specific molecule linking...
