RPL554

Verona’s lead drug, RPL554, is a dual phosphodiesterase (PDE) 3 and 4 inhibitor being developed as a novel treatment for chronic obstructive airways disease as COPD (chronic obstructive pulmon...

Kadcyla (ado-trastuzumab emtansine)

Kadcyla™ (ado-trastuzumab emtansine or T-DM1) for the treatment of people with HER2-positive metastatic breast cancer (mBC) who have received prior treatment with Herceptin® (trastuzumab)...

Gastrointestinal Effects

Immunocytokines

Although the human cytokines interleukin-2 (IL-2) and tumor necrosis factor (TNF) alpha are approved marketed for tumor therapy, their use is rather limited due to severe systemic side effects. Targ...

Adverse drug effects

Will ‘Side Effects’ Have Side Effects For Pharma?

There have been several movies over the years that have, in various ways, focused on the pharmaceutical industry and the latest to do so is ‘Side Effects,’ the Steve Soderbergh film that d...

University of Colorado Cancer Center Review Shows Long-term Side-effects of New, Targeted Therapies in Pediatric Cancer Patients

Aurora, COLO (PRWEB) February 07, 2013 A University of Colorado Cancer Center review published this week in the journal Lancet Oncology describes possible long-term side-effects of new, targeted th...

I want it said of me by those who knew me best, that I always plucked a thistle and planted a flower where I thought a flower would grow.

Abraham Lincoln,16th U.S. president -More- 

Statin Side Effects Are Usually Overcome

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

Statin Therapy Side Effects Go Away With Persistence

Statin side effects commonly make people discontinue treatment, but most patients who go back to them overcome the side effects and remain on their medication long term, researchers from Brigham and W...

CSHL-led team discovers new way in which plants control flower production

(Cold Spring Harbor Laboratory) The timing of flowering in plants is critical. It can have profound effects on flower, fruit, and seed production, and consequently agricultural yields. This process is...

SNPing side effects: Sidebar: Inform Genomics Inc. Corporate Profile

SNPing side effects Inform Genomics Inc. Boston, Mass. Technology: SNP-based test to predict chemotherapy side effects Disease focus: Diagnostic Clinical status: NA Founded: 2010 by Ed Rubenstein, Sus...

Finally! An Answer To A Good Nights Sleep

Adelaide, Australia (PRWEB) January 22, 2013 There are many products on the market that claim to help you 'sleep'. The majority of these pills and potions are sedative based products that c...

Is the flower fluorescence relevant in biocommunication?

Flower fluorescence has been previously proposed as a potential visual signal to attract pollinators. In this work, this point was addressed by quantitatively measuring the fluorescence quantum yield...

Downregulation of putative UDP-glucose: flavonoid 3-O-glucosyltransferase gene alters flower coloring in Phalaenopsis.

Anthocyanin is the primary pigment contributing to red, violet, and blue flower color formation. The solubility of anthocyanins is enhanced by UDP glucose: flavonoid 3-O-glucosyltransferase (UFGT) thr...

Inheritance and Epistasis of Loci Influencing Carotenoid Content in Petal and Pollen Color Variants of California Poppy (Eschscholzia californica Cham.).

The model basal eudicot plant California poppy (Eschscholzia californica Cham.) typically has intense yellow to orange petals and orange pollen due to pigmentation by carotenoids. Flower color variant...

Characterization of a heavy-ion induced white flower mutant of allotetraploid Nicotiana tabacum.

KEY MESSAGE : We characterized a white flower mutant of allotetraploid N. tabacum as a DFR-deficient mutant; one copy of DFR has a cultivar-specific frameshift, while the other was deleted by heavy-io...

Metabolomic profiling of the flower bud and rachis of Tussilago farfara with antitussive and expectorant effects on mice.

Flower bud of Tussilago farfara L. is widely used for the treatment of cough, bronchitis and asthmatic disorders in the Traditional Chinese Medicine. However, due to the increasing demands, adulterati...