Search Results for "Hplc Method Optimisation"
Original Source: Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities.
The European Pharmacopoeia describes a liquid chromatography (LC) method for the quantification of sulindac, using a quaternary mobile phase including chloroform and with a rather long run time. In the present study, a new method using a short sub-2 μm column, which can be used on a classical HPLC system, was developed. The new LC conditions (without chloroform) were optimised by means of a new methodology based on design of experiments in order to obtain an optimal separation. Four factors were studied: t...
Matching Channels
Fluorescent in situ hybridization (FISH) is a sensitive and accurate technique that allows the detection of chromosome aberrations. In this method, a single-stranded fluorescent-labeled nucleic acid...
The gold standard in lung testing In the same way that blood pressure measurements provide a simple yet effective screening method for cardiovascular disease, spirometry tests can help to unmask t...
Drug Delivery - news, views, blogs
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulat...
Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2
Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...
Testicular cancer represents only 1 per cent of all cancers in men, but it is the single biggest cause of cancer-related deaths in men aged 15-35 years in the UK. The causes of testicular cancer and...
Matching News
The Hamilton PRP™-C18 Reversed-Phase HPLC Column is designed to increase the accuracy and quality of separations performed by pharmaceutical companies, environmental scientists, and others.Read more...
Porvair Sciences Speeds Up Evaporation of HPLC Solvents
Combining a new 48-well needle head with a dedicated HPLC vial holder that accepts 48 standard 1.5ml vials transforms any MiniVap or UltraVap system into a high throughput HPLC sample evaporator.
HPLC Assay of Gentamicin Sulfate Congeners in Just 15 Minutes
Thermo Fisher Scientific is pleased to announce a direct-detection reversed-phase high-performance liquid chromatography (HPLC) chromatographic assay method that separates the congeners in gentamic...
HPLC Column Streamlines Productivity
Hamilton Company's Laboratory and Sensor Products Division has introduced the Hamilton PRP-C18 reversed-phase HPLC column, designed to increase accuracy of separations performed by pharmaceutical comp...
Provair Sciences has introduced a new version of its MiniVap and UltraVap blowdown evaporators that use warm air or nitrogen to speed up the evaporation of common HPLC solvents such as dichloromethan...
Thermo Fisher Scientific has announced that its Syncronis HPLC columns are now available with 3 mm particle size. The new particle size complements the existing 1.7 and 5 mm particle sizes.Read more...
Medicines optimisation may be “the new kid on the block” but it is definitely here to stay. What does it mean? What is it?
HPLC analytical method development and validation
13 - 14 June 2013 Training Course Amsterdam, The Netherlands
Matching PubMed Articles
The European Pharmacopoeia describes a liquid chromatography (LC) method for the quantification of sulindac, using a quaternary mobile phase including chloroform and with a rather long run time. In th...
In this study, chemometric predictive models were developed from near infrared (NIR) spectra for the quantitative determination of saturates, aromatics, resins and asphaltens (SARA) in heavy petroleum...
Betamethasone Sodium Phosphate and Betamethasone Acetate are the two corticosteroids active pharmaceutical ingredients (APIs) that are present in the injectable formulation, Celestone Chronodose(®) I...
The manuscript presents the development of a new reverse phase high performance liquid chromatography (RP-HPLC) photo diode array detection method allowing the separation and quantification of 15 caro...
A simple and rapid analytical procedure was proposed for the determination of chromatographic peaks by means of partial least squares multivariate calibration (PLS) of high-performance liquid chromato...
