Search Results for "Hpv Celecoxib Trial"
Original Source: Celebrex (Celecoxib) Treatment of Laryngeal Papilloma
Respiratory recurrent papilloma (RRP) is one of the most common benign tumors. Surgical removal is the current management for RRP, but it is a very traumatic procedure, and often leads to permanent voice dysfunction. In this study, we will develop a new, combined RRP treatment with a pulsed dye laser (PDL) and Celecoxib. We will determine if Celecoxib, a newly developed inhibitor of cyclooxygenase (COX)-2, can provide a long-term inhibitory effect on RRP, therefore preventing R...
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ATX-MS-1467 for patients with multiple sclerosis (MS)
ATX-MS-1467 is a novel treatment that was developed with the aim of working with the immune system to treat the underlying cause of disease rather than just treating the symptoms or suppressing the...
Clinical Approvals - news, views, reports and blogs
Clinical trials are a set of procedures in medical research conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and eff...
Xofigo (radium-223 dichloride)
New treatment for castration-resistant prostate cancer (CRPC) patients with bone metastases. Xofigo shown in a pivotal phase III trial to significantly improve overall survival. Xofigo® with...
Research has not found any adverse effects from consuming vitamin E in food. However, high doses of alpha-tocopherol supplements can cause hemorrhage and interrupt blood coagulation in animals, and...
Contract Research Organization news
A contract research organization, also called a clinical research organization, (CRO) is a service organization that provides support to the pharmaceutical and biotechnology industries in the form o...
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Prostate cancer: Celecoxib trampled in the STAMPEDE trial
Initial results from the STAMPEDE trial of androgen deprivation therapy with and without celecoxib in patients with prostate cancer have shown that celecoxib does not confer benefit. Despite this nega...
Pfizer Says Celecoxib Meets Primary Objective In Phase 4 Clinical Trial
NEW YORK CITY (dpa-AFX) - Pfizer Inc. (PFE) announced top-line results in which Celecoxib met primary objective in clinical trial to evaluate the effects on blood pressure in pediatric patients wi...
AAPS PharmSciTech: Influence of Microcrystal Formulation on In Vivo Absorption of Celecoxib in Rats
Type: Original PaperThe objective of this study was to prepare celecoxib microcrystals using different stabilizers in order to evaluate the influence of microcrystal formulation on the in vitro dissol...
Effects of Celecoxib on Restenosis After PCI
For angina patients receiving drug-eluting stents, does celecoxib have a big enough impact on late loss outcomes to offset the risk? European Heart Journal
Pfizer delays generic celecoxib entry in US
Pharma giant Pfizer announced on 5 March 2013 that the US Patent Office had given the company an extra 18 months of exclusivity for its blockbuster anti-inflammatory painkiller Celebrex (celecoxib).
[Corrections] Correction to Lancet Oncol 2012; 13: 549, 554
James ND, Sydes MR, Mason MD, et al, for the STAMPEDE investigators. Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE...
Iroko reports Phase III pain data for submicron indomethacin
Iroko Pharmaceuticals LLC (Philadelphia, Pa.) said in a Phase III trial to treat post-surgical acute pain that all three doses of submicron indomethacin met the primary endpoint of reducing pain inten...
Pfizer Inc. announced today that the United States Patent & Trademark Office has granted Pfizer a reissue patent (U.S. Patent No. RE44048), covering methods of treating osteoa...
Matching PubMed Articles
Abstract: Objectives: The NICE health economic model for assessing the cost-effectiveness of celecoxib plus a proton pump inhibitor (PPI) compared to diclofenac plus PPI in the treatment of osteoa...
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor with antitumor and antiangiogenic activities. To investigate the effects of celecoxib on nasopharyngeal carcinoma (NPC), HNE-1 cells were tr...
Obsessive-compulsive disorder is a common neuropsychiatric condition. Although a variety of pharmaceutical agents is available for its treatment, psychiatrists have found that many patients cannot tol...
The use of chitosan as the wall of microcapsule designed for delivery of encapsulated celecoxib is reported. Microcapsules were characterised with respect to size and encapsulation efficiency of celec...
Molecular dynamics and physical stability of amorphous anti-inflammatory drug: celecoxib.
By using dielectric spectroscopy we analyzed the relation between molecular mobility and tendency of the amorphous celecoxib to recrystallize. We found that celecoxib is kinetically a fragile glassfor...
