Search Results for "Hrg Platelet"
Original Source: Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH Campus
Plasma histidine-rich glycoprotein (HRG) binds to platelets in the presence of zinc (1). This binding is totally blocked by a monoclonal antibody directed against platelet membrane CD36. Therefore, CD36 is assumed to carry the platelet binding site for HRG (2). Because CD36 also has a variety of other ligands, including polyanionic lipids, it is also possible that it contains the binding site for heparin (also polyanionic) and might be involve in the pathogenesis of heparin-...
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Low-dose prasugrel reduces high on-clopidogrel platelet reactivity in elderly
NEW YORK (Reuters Health) - In older patients with acute coronary syndrome (ACS) and high on-clopidogrel platelet reactivity, reduced-dose prasugrel (5 mg/d) was significantly more effective than...
Platelet Concentration System Optimizes Conditions for Healing
An updated platelet concentration system produces platelet rich plasma, a blood plasma with highly concentrated platelets that also contain...
Healthy People Harmed By Platelet Activation Caused By Passive Smoking
"It is well known that passive smoking is harmful for cardiovascular health, but the mechanism has not yet been discovered," said Dr Kaya. "We investigated the effects of passive smoking on the levels...
Hematology Analyzers Offer Channel for Immature Platelet Fraction
AACC 2012: A hematology analyzer includes a fluorescent platelet channel for Immature Platelet Fraction, which will aid in...
Back to the Drawing Board for Platelet Monitoring
A TRILOGY substudy has found no independent association of platelet function and ischemic outcomes in medically managed ACS patients. Meanwhile, the ARCTIC trial found no benefit of platelet-function...
Prasugrel (Effient) vs Ticagrelor (Brilinta) in Primary PCI
The Rapid Activity of Platelet Inhibitor Drugs Study showed that four hours is needed to achieve effective platelet inhibition in most patients, with just 50% of treated patients having effective...
ESC: Platelet Tests Guide Post Stenting Tx (CME/CE)
MUNICH (MedPage Today) -- A pair of observational studies may boost lagging enthusiasm for platelet function testing, researchers reported here.
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2B or not to be - The 45-year saga of the Montreal Platelet Syndrome.
Over 45 years ago, Montreal Platelet Syndrome was first described as a rare inherited platelet disorder characterised by macrothrombocytopenia with spontaneous platelet clumping, abnormal platelet sha...
A case of Quebec platelet disorder is hereby reported. A 33 years old woman presented with history of epistaxis and gum bleeding since childhood and menorrhagia and bleeding per vaginum after puberty,...
Effect of Hemodynamic Forces on Platelet Aggregation Geometry.
The shear rate dependence of platelet aggregation geometries is investigated using a combination of in vitro and numerical experiments. Changes in upstream shear rate, γ(Pw), are found to cause syste...
Brief Report: Platelet-Poor Plasma Serotonin in Autism.
Possible explanations for the well-replicated platelet hyperserotonemia of autism include an alteration in the platelet's handling of serotonin (5-hydroxyserotonin, 5-HT) or an increased exposure of t...
Progress in diagnostic evaluation of platelet function disorders.
Both for diagnosis of congenital and acquired platelet dysfunction as well as for therapy monitoring after application of platelet function inhibitors various methods have been established for evaluat...
