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08:11 EDT 30th July 2015 | BioPortfolio

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Freiberg Infraction

Freiberg's disease is an osteochondrosis of the metatarsal head, most commonly occurring in young athletes older than 12 years who perform on their toes in either sprinting or jumping activities...

Pediculosis - louse (lice) treatment

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Pediculosis - louse (lice) infestation

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Pediculosis - louse (lice) diagnosis

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G-protein-coupled receptors (GPCRs)

GPCRs are a large family of cell surface receptors that respond to a variety of external signals. Binding of a signaling molecule to a GPCR results in G protein activation, which in turn triggers th...

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Oxford provides up to $21mm in debt financing to ADMA Biologics

Oxford Finance provided infectious disease-focused ADMA Biologics Inc. with an initial $16mm loan to repay an existing loan. ADMA has the option to draw down another $5mm upon the approval of its BLA ...

Esperion hits record high on ETC-1002 results

Shares of Esperion Therapeutics Inc. (NASDAQ:ESPR) jumped $22.50 (29%) to $99.60, hitting an all-time high on Tuesday after the company said ETC-1002 met the primary endpoint of lowering LDL-cholester...

ADMA Biologics nets $9.2mm via FOPO

Infectious disease-focused ADMA Biologics Inc. netted $9.2mm through the follow-on offering of 1.2mm common shares at $8 each. Proceeds will help fund the anticipated launch of its lead antibody candi...

ADMA Biologics nets $10.6mm via FOPO

Infectious disease-focused ADMA Biologics Inc. netted $10.6mm through the follow-on offering of 1.4mm common shares (including the overallotment) at $8 each. Proceeds will help fund the anticipated la...

Esperion Therapeutics Announces Positive Top-Line Phase 2b Results for ETC-1002 Added to Stable Statin Therapy in Patients With Hypercholesterolemia

ANN ARBOR, MI--(Marketwired - March 17, 2015) - Esperion Therapeutics, Inc. (NASDAQ: ESPR), an emerging pharmaceutical company focused on developing and commercializing first-in-class, oral low-densit...

ADMA completes debt financing

ADMA Biologics Inc completes follow-on

First Look: Esperion Study 008 Full Results

On Saturday, March 14, 2015, Esperion investigators presented the full results from Study 008 at the American College of Cardiology 64th Annual Scientific Session. This is being accomplished through a...

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First-Trimester Maternal Serum Levels of sFLT1, PGF and ADMA Predict Preeclampsia.

Placental growth factor (PGF), soluble fms-like tyrosine kinase 1 (sFLT1) and asymmetric dimethylarginine (ADMA) are involved in the pathogenesis of preeclampsia. Abnormal maternal sFLT1, PGF and ADMA...

Physical exercise reduces synthesis of ADMA, SDMA, and L-Arg.

Increased levels of asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and low plasma level of L-arginine (L-ARG) are all conditions likely to decrease nitric oxide (NO) production....

Endothelial DDAH1 is an Important Regulator of Angiogenesis but Does Not Regulate Vascular Reactivity or Hemodynamic Homeostasis.

-Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthesis and a risk factor for cardiovascular disease. Dimethylarginine dimethylaminohydrolase (DDAH) enzymes are respon...

Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles.

Multidrug resistance (MDR) presents a clinical obstacle to cancer chemotherapy. The main purpose of this study was to evaluate the potential of a hyaluronic acid (HA) and α-tocopheryl succinate (α-T...

Reduced Renal Methylarginine Metabolism Protects against Progressive Kidney Damage.

Nitric oxide (NO) production is diminished in many patients with cardiovascular and renal disease. Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of NO synthesis, and elevated plasma le...

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