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Freiberg's disease is an osteochondrosis of the metatarsal head, most commonly occurring in young athletes older than 12 years who perform on their toes in either sprinting or jumping activities...
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GPCRs are a large family of cell surface receptors that respond to a variety of external signals. Binding of a signaling molecule to a GPCR results in G protein activation, which in turn triggers th...
* CRL did not cite any concerns with clinical safety and efficacy data for ri-002 submitted by adma in bla
The US Food and Drug Administration (FDA) has issued a Complete Response Letter (CRL) to the ADMA Biologics' Biologics License Application (BLA) for RI-002, an Intravenous Immune Globulin (IVIG), for ...
The latest drug development news and highlights from our FDA Performance Tracker.
* Expects to report topline six-month data from Duchenne muscular dystrophy trial on CAP-1002 in Q1 of 2017 Source text for Eikon: Further company coverage:
RAMSEY, N.J., Aug. 12, 2016 (GLOBE NEWSWIRE) -- ADMA Biologics, Inc. (NASDAQ:ADMA), a late-stage biopharmaceutical company that develops, manufactures, and intends to commercialize specialty plas...
RAMSEY, N.J., Nov. 10, 2016 (GLOBE NEWSWIRE) -- ADMA Biologics, Inc. (NASDAQ:ADMA), a late-stage biopharmaceutical company that develops, manufactures, and intends to commercialize specialty plas...
RAMSEY, N.J., Sept. 01, 2016 (GLOBE NEWSWIRE) -- ADMA Biologics, Inc. (NASDAQ:ADMA), a late-stage biopharmaceutical company that develops, manufactures, and intends to commercialize specialty pla...
Elevated plasma concentrations of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA) have been observed in respiratory conditions such as asthma and cystic fibrosi...
Hormonal, neurogenic, vasculogenic, and psychogenic impairments, as well as endothelial dysfunction may play a role in erectile dysfunction (ED) in patients with chronic kidney disease (CKD). Asymmetr...
Cognitive deficits are a core feature of schizophrenia. Previous studies have shown that plasma asymmetric dimethylarginine (ADMA), an endogenous inhibitor of the nitric oxide synthase, was increased ...
Hypertensive left ventricular hypertrophy (LVH) is a maladaptive response to chronic pressure overload and a strong independent risk factor for cardiovascular disease. Regression of LVH is associated ...
Increased oxidative stress in diabetes increases nitric oxide (NO) oxidation and low L-arginine (Arg) could further reduce NO and impair vascular function, thus accelerating, in the long run, vascular...