Search Results for "Http Www Bioportfolio Com Channels Abbott"
Matching Channels
PKC (protein kinase C) http://www.bioportfolio.com/channels/serine-threonine-protein-kinase-c-pkc is a kinase enzyme and a protein molecule that can change the format of other proteins through chemi...
The 11th largest pharmaceutical company in the world, Abbott Laboratories generated sales of $16 billion in 2009 and has 90,000 employees. Within the medical device arm of the company, products of...
Myc is the protein encoded by the MYC gene that activates the cell cycle
Myc is the protein encoded by the MYC gene that activates the cell cycle. It promotes cell replication through genetic coding for p14, inhibiting MDM2 and preventing the degradation of the pro-apopt...
APC stands for adenomatous polyposis coli, a form of colorectal cancer and is a tumour suppressor
APC stands for adenomatous polyposis coli, a form of colorectal cancer and is a tumour suppressor. When APC it mutated, it can cause this particular type of colorectal cancer. When not present in it...
Matching News
Latest Cystic Fibrosis Market Reports on BioPortfolio.net
Our key pages for cystic fibrosis reports are packed with useful information and links to the latest cystic fibrosis market reports from over 30 of the worlds leading market research companies which...
Latest Oncology Market Research on BioPortfolio.net
Reports on the global oncology market are now available for purchase from BioPortfolio.net following a redesign and reconfiguration of key pages on the leading biotechnology, healthcare and pharmace...
31st August 2011: BioPortfolio - the life science portal adds HTStec's new report to biotechnology research store: Pathway Analysis - Signal Transduction - Trends 2011. HTStec's P...
Abbott Holding Steady For Long-Term Investments
By ValueMax:Abbott Laboratories (ABT) is currently one of the most appealing investments in the Big Pharma sector. Abbott continues to increase applications for its industry leading rheumatoid arthrit...
Abbott Challenges Biosimilar Legality
This from today's Xconomy. Abbott has filed a citizen's petition with the FDA to protect Humira by challenging the notion that the agency can refer to Abbott's Humira BLA filing. Their argument (poste...
Abbott's AbbVie spinout debuts
The AbbVie Inc. (NYSE:ABBV) pharmaceutical business spinout of Abbott Laboratories (NYSE:ABT) debuted on Wednesday as a separate public company. Abbott retains Abbott's name and houses the pharma's ge...
Model-independent way to study ion channel gating
Two studies in The Journal of General Physiology (JGP) help pave the way for a "shortcut" model-free approach to studying activation of "polymodal" ion channels-channels that open in response to multi...
TEXT-S&P may still cut Abbott Laboratories ratings
Overview -- U.S. diversified pharmaceutical company Abbott Laboratories intends to split off its global proprietary pharmaceutical operations into a separate company, to be named AbbVie, lea...
Matching PubMed Articles
Abbott Physicochemical Tiering (APT)-A unified approach to HTS triage.
The selection of the highest quality chemical matter from high throughput screening (HTS) is the ultimate aim of any triage process. Typically there are many hundreds or thousands of hits capable of m...
Exploration of diverse hinge-binding scaffolds for selective Aurora kinase inhibitors.
Four hinge-binding scaffolds have been explored for novel selective Aurora kinase inhibitors. The structure activity relationship, selectivity and pharmacokinetic profiles have been evaluated.
Assessing renal function: Some significant improvements on the horizon.
A series of compounds was designed as dual inhibitors of the H(3) receptor and the norepinephrine transporter. Compound 5 (rNET K(i) = 14 nM; rH(3)R K(i) = 37 nM) was found to be efficacious in a rat...
Discovery of diphenyl lactam derivatives as N-type calcium channel blockers.
A novel series of diphenyl lactam containing calcium channel blockers is described. Extensive SAR studies resulted in compounds with low molar activity and good plasma exposure after oral dosing. Comp...
