Search Results for "Hydralazine Syndrome"
Original Source: Hydralazine-Induced Pulmonary-Renal Syndrome: A Case Report.
Drug-induced lupus erythematosus differs in its manifestation from drug-induced vasculitis. The former is associated with characteristic symptoms that improve following discontinuation, whereas the latter is predominantly an antineutrophil cytoplasmic antibody (ANCA) positive small vessel vasculitis involving the kidneys, skin, and lungs. We present a case of advanced disease in an elderly Caucasian woman requiring corticosteroids, and immunosuppressive therapy, who was on hydralazine for >2 years. A 75-yea...
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Tumorigenesis in Down's syndrome: big lessons from a small chromosome
Individuals with Down's syndrome have an increased risk of developing leukaemia in childhood, but they also have a significantly reduced risk of developing most solid tumours. However, Down's syndrome...
Learning Deficit Reduced By Prenatal Intervention In Mice, Down Syndrome Characteristics Improved
Mice with a condition that serves as a laboratory model for Down syndrome perform better on memory and learning tasks as adults if they were treated before birth with neuroprotective peptides, accordi...
Settings standards for research into Rett syndrome
(International Rett Syndrome Foundation) There is an urgent need for new drugs to treat Rett syndrome, a rare and severe neurological disease mainly affecting girls. A bottleneck in drug development f...
Molecular roots of Down syndrome unraveled
What is it about the extra chromosome inherited in Down syndrome -- chromosome 21 -- that alters brain and body development? Researchers have new evidence that points to the protein SNX27. SNX27 is in...
New Method For Detecting Fetal Down Syndrome And Edwards Syndrome Shows Promise
A new study, published online in the American Journal of Obstetrics and Gynecology states that false positive and false negative results have been produced by current Down syndrome and Edwards syndrom...
Metabolic Syndrome Affects Cognition in Obese Teens
Obese teens with metabolic syndrome score lower on IQ, spelling, and math tests than their counterparts who do not have metabolic syndrome. Medscape Medical News
Mutations in the TGF-β repressor SKI cause Shprintzen-Goldberg syndrome with aortic aneurysm
Harry Dietz and colleagues report the identification of mutations in SKI in Shprintzen-Goldberg syndrome, which shares features with Marfan syndrome and Loeys-Dietz syndrome. SKI encodes a known repre...
Lithium restores cognitive function in Down syndrome mice
Down syndrome is a neurodevelopmental disorder that is the leading cause of genetically defined intellectual disability. In the brain, Down syndrome results in alterations in the connections between n...
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AIM: To investigate the effect of intravenous hydralazine infusion on maternal nitric oxide (NO) levels. METHODS: Th...
Hydralazine-Induced Pulmonary-Renal Syndrome: A Case Report.
Drug-induced lupus erythematosus differs in its manifestation from drug-induced vasculitis. The former is associated with characteristic symptoms that improve following discontinuation, whereas the la...
Hydralazine modifies aβ fibril formation and prevents modification by lipids in vitro.
Lipid oxidative damage and amyloid β (Aβ) misfolding contribute to Alzheimer's disease (AD) pathology. Thus, the prevention of oxidative damage and Aβ misfolding are attractive targets for drug dis...
Hydralazine for essential hypertension.
BACKGROUND: Hypertension is associated with an increased risk of stroke, myocardial infarction and congestive heart failure. Hydralazine is a direct-acting vasodilator which has been used for the trea...
Activation of the renin-angiotensin system (RAS) is thought to promote myocardial fibrosis. However, it is unclear whether this physiological fibrotic response results from chronic hemodynamic stress...
