Herpes simplex virus HSV 1 HSV 2 HHV 1 HHV 2

Herpes simplex virus 1 and 2 (HSV-1 and HSV-2), also known as Human herpes virus 1 and 2 (HHV-1 and -2), are two members of the herpes virus family that infect humans. HSV-1 and HSV-2 cause the vira...

Ibuprofen-Famotidine Combination Reduces Ulcer Risk

Combining ibuprofen and famotidine into 1 pill can control pain while lowering the risk for ulcers posed by ibuprofen alone. Medscape Medical News

GPhA: 'Up-scheduling' hydrocodone combos will impede patient access, won't curb abuse

Ahead of a two-day meeting of the FDA's Drug Safety and Risk Management Advisory Committee (DSaRM), in which regulators are seeking advice about whether to "up-schedule" hydrocodone combination medi...

DEA agent to FDA safety panel: Hydrocodone combos are 'killing us'

Drug safety advisers to the US FDA heard arguments from both ends of the spectrum on 24 January about the impact to patients and society if hydrocodone combination medicines, like Vicodin (acetaminop...

SPI Pharma launches Actimask Ibuprofen 92S

SPI Pharma, Inc., a global leader in providing pharmaceutical ingredients and technologies for patient-friendly dosage forms, announces the launch of Actimask Ibuprofen 92S, a taste-masked Ibuprofen.

AAPA and AANP Comment on FDA Hydrocodone Recommendation

A recent recommendation by a Food and Drug Administration (FDA) panel about hydrocodone elicited responses from American Association of Nurse Practitioners president Angela Golden, DNP, FNP-C, FAANP,...

FDA panel votes for tougher restrictions on hydrocodone

(HealthDay)—A U.S. Food and Drug Administration advisory panel met Thursday and Friday to discuss the fate of certain painkillers that contain the opioid known as hydrocodone, concluding in a vote i...

FDA panel backs tougher restrictions for hydrocodone products

FDA's Drug Safety and Risk Management Advisory Committee voted 19-10 on Friday that the U.S. Drug Enforcement Administration (DEA) reschedule hydrocodone combination products as class II scheduled dru...

Is Zogenix A Buy After FDA Panel Says 'No' To Zohydro?

ByC.R. Jackson:Zogenix Inc., (ZGNX) is the first pharmaceutical company to face a U.S. Food and Drug Administration (FDA) panel seeking approval for pure hydrocodone, a painkilling drug that can be 10...

Anomalous observations of hydrocodone in patients on oxycodone.

BACKGROUND: Urine drug monitoring is used by physicians treating chronic pain patients with opioid therapy. Patients are tested in part to insure that they are not taking other drugs. Therefore, the f...

Hydrocodone and morphine possess similar rewarding effects and reduce ERK and CREB phosphorylation in the nucleus accumbens.

The number of prescriptions for hydrocodone-containing opioid analgesics has greatly increased over the past decade. This increase has led to an associated enhancement in the non-medical use of hydroc...

Update on hydrocodone metabolites in rats and dogs aided with a semi-automatic software for metabolite identification Mass-MetaSite.

1. There has been a lack of in vivo metabolite profiling update of hydrocodone since the original report on species differences was published in 1978. As such, the mechanism for its analgesic activity...

Ibuprofen-phospholipid solid dispersions: Improved dissolution and gastric tolerance.

Solid dispersions of ibuprofen with various phospholipids were prepared, and the effect of phospholipids on the in vitro dissolution and in vivo gastrointestinal toxicity of ibuprofen was evaluated. M...

Development of novel ibuprofen-loaded solid dispersion with enhanced bioavailability using cycloamylose.

To develop a novel ibuprofen-loaded solid dispersion with enhanced bioavailability using cycloamylose, it was prepared using spray-drying techniques with cycloamylose at a weight ratio of 1:1. The eff...