Prostate specific membrane antigen PSMA

Prostate-specific membrane antigen (PSMA) is a transmembrane protein commonly found on the surface of late-stage and metastatic prostate cancer and a well-known imaging biomarker for staging and monit...

Mumps Skin Test Antigen

Tumor Antigen-KLH Vaccine rDNA

Human Leukocyte Antigen HLA System

AntigenPresenting Cells

[Tetragenetics] uses its {TetraExpress} to express [Amgen] antigen

[Tetragenetics Inc.] (focused on ion channel therapeutics) has agreed to use its {TetraExpress} Tetrahymena thermophile-based technology to express a surface antigen that [Amgen Inc.] has selected....

Monoclonal Antibodies to the Tumor-Specific Antigen, Human ROR1

B-cell chronic lymphocytic leukemia (B-CLL) is an incurable disease developed by more than 15,000 Americans each year and currently, there are no therapeutic monoclonal antibodies (mAbs) that specific...

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

B cells regulate immune responses by producing antigen-specific antibodies. However, specific B-cell subsets can also negatively regulate T-cell immune responses, and have been termed regulatory B cel...

Human medicines European Public Assessment Report (EPAR): Focetria, influenza vaccine (H1N1) (surface antigen, inactivated, adjuvanted), Revision: 8, Authorised

Human medicines European Public Assessment Report (EPAR): Aflunov, prepandemic influenza vaccine (H5N1) (surface antigen, inactivated, adjuvanted), Revision: 2, Authorised

Human medicines European Public Assessment Report (EPAR): Optaflu, Influenza vaccine (surface antigen, inactivated, prepared in cell cultures), Revision: 5, Authorised

Human medicines European Public Assessment Report (EPAR): Foclivia, pandemic influenza vaccine (H5N1) (surface antigen, inactivated, adjuvanted), Revision: 1, Authorised

Smart-lg: Novel antibody recycling technology by engineering endosomal antigen dissociation

SMART-Ig, Sequential Monoclonal Antibody Recycling Technology Immunoglobulin, enables a single antibody to bind to the antigen multiple times by pH-dependent antigen dissociation within acidic endosom...

Genetically Encoded pH Sensor for Tracking Surface Proteins through Endocytosis.

Traffic cam: A tandem dye prepared from a FRET acceptor and a fluorogenic donor functions as a cell surface ratiometric pH indicator, which upon internalization serves to follow protein trafficking...

Small Molecule Inhibitors of Anthrax Toxin-Induced Cytotoxicity Targeted Against Protective Antigen.

Two molecular scaffolds were designed using the CAVEAT molecular design package to inhibit the oligomerization of protective antigen (PA(63) ), a key protein component of anthrax toxin. The inhibitors...

Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells.

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain, reduce fever and inhibit inflammation. NSAIDs function mainly through inhibition of cyclooxygenase (COX). Gro...

Antigen adsorbed surface modified poly-ɛ-caprolactone microspheres stimulates both adaptive and innate immune response in fish.

Surface modified poly-ɛ-caprolactone microspheres as an antigen carrier was explored in a fish model. Outer membrane vesicles of Edwardsiella tarda adsorbed on to surface modified poly-ɛ-caprolacton...

Blood groups and susceptibility to virus infection: new developments.

PURPOSE OF REVIEW: Histo-blood group antigens belonging to the P1PK and GLOB blood group systems are involved in bacterial infections, but a substantial body of evidence is emerging that some of these...