Search Results for "Intrapertoial Injection Of Doxorubicin To Rat"
Original Source: Detection of doxorubicin hydrochloride accumulation in the rat brain after morphine treatment by mass spectrometry.
PURPOSE: The blood-brain barrier discriminates the access of several molecules to the brain. This hampers the use of some drugs, as doxorubicin, potentially active for treatment of brain tumors. We explored the feasibility of active modification of the blood-brain barrier protection, by using morphine pretreatment, to allow doxorubicin accumulation in the brain in an animal model. METHODS: Rats were pretreated with different doses of intraperitoneal morphine before injection of doxorubicin (12 mg/kg). Quant...
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Intracytoplasmic sperm injection
KYNAMRO (mipomersen sodium) injection is an oligonucleotide inhibitor of apolipoprotein B-100 synthesis indicated as an adjunct to lipid-lowering medications and diet to reduce low density lipoprote...
Drug Delivery - news, views, blogs
Drug delivery is the method or process of administering a pharmaceutical compound to achieve a therapeutic effect in humans or animals. Drug delivery technologies are patent protected formulat...
Hepatitis B Immune Globulin Cangene
HepaGam B® [Hepatitis B Immune Globulin (Human) Injection] contains purified antibodies specific for the hepatitis B surface antigen (HBsAg). * It is approved in Canada and the United States f...
What is GENOTROPIN? GENOTROPIN (somatropin [rDNA origin] for injection) is a growth hormone treatment. It is an exact copy of the natural growth hormone that our bodies make. The main difference i...
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Type: Original PaperThe purpose of this study was to examine doxorubicin adsorption in polypropylene containers as a function of pH and drug concentration based on anecdotal evidence of such adsorptio...
Identification of the molecular basis of doxorubicin-induced cardiotoxicity
Doxorubicin, which induces tumor cell death through effects on topoisomerase-II, is a commonly used chemotherapeutic agent but has the substantial drawback of causing cardiotoxicity. Edward T.H.Yeh an...
FDA approves Sun Pharma ANDA for generic Doxil
The US Food and Drug Administration (FDA) has approved Sun Pharmaceutical Industries' abbreviated new drug application (ANDA) for Doxorubicin HCl Liposome Injection USP, 2 mg/ml.
Sun Pharma receives FDA approval for generic Doxil
The U.S. Food and Drug Administration today approved the first generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection).
Doxorubicin cardiotoxicity same with continuous or bolus infusion
NEW YORK (Reuters Health) - Researchers who tried giving doxorubicin to kids with acute lymphoblastic leukemia (ALL) via continuous infusion instead of boluses, to minimize the cardiotoxic effects...
Doxorubicin-eluting beads improve HCC outcomes
NEW YORK (Reuters Health) - Unresectable hepatocellular carcinoma (HCC) responded more often to transarterial chemoembolization (TACE) when doxorubicin-eluting beads were used, in a recent retrosp...
Generic Doxil approval may help alleviate drug shortages
FDA announced on 4 February 2013 that the agency had approved the first generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection).
Ziopharm completes enrollment in PICASSO 3 trial
Ziopharm Oncology has completed enrollment in PICASSO 3 trial of palifosfamide in combination with doxorubicin, versus doxorubicin alone, for the treatment of metastatic soft tissue sarcoma (STS) in t...
Matching PubMed Articles
Photoinduced reactivity of Doxorubicin: catalysis and degradation.
Doxorubicin exhibits unusual photoreactivity in aqueous solutions. Our data show that there are two distinct photoreactive pathways for doxorubicin. One is a two-step process that leads to the formati...
Inhalable nanoparticles, a non-invasive approach to treat lung cancer in a mouse model.
Doxorubicin-loaded nanoparticles (NPs) were incorporated into inhalable effervescent and non-effervescent carrier particles using a spray-freeze drying technique. The prepared inhalable powders were t...
Zirconium phosphate nano-platelets: a novel platform for drug delivery in cancer therapy.
Doxorubicin was intercalated into novel zirconium phosphate nano-platelets (ZrP). The obtained doxorubicin intercalated ZrP nano-platelets had an impressive 34.9% (w/w) drug loading. We used this mate...
The protective effect of eugenol and its possible mechanisms were investigated in rats with acute doxorubicin cardiotoxicity. Cardiac toxicity was induced by a single intraperitoneal injection of doxo...
PPAR-α transcriptional activity is required to combat doxorubicin-induced podocyte injury in mice.
Immunosuppressants and inhibitors of the renin angiotensin system are major reagents to treat nephrotic syndrome but their clinical effects are not necessarily satisfactory. Injection of doxorubicin i...
