Iron

Iron absorption

Iron deficiency

Iron Overload

Secondary Iron Overload

Simultaneous structure–activity studies and arming of natural products by C–H amination reveal cellular targets of eupalmerin acetate

Natural products are enduring leads for exploring cell biology, yet structure–activity relationship studies and 'arming' of these small molecules for subsequent cellular probe synthesis remains a ch...

Personal Health: Iron Deficiency and Iron Overload

Concerns about iron deficiency have eased with the wide availability of iron-fortified foods and drinks. Now more attention is being paid to the opposite problem: iron overload, which can cause seriou...

Scientists identify aromatic rice with very low arsenic content

Millions of people worldwide are regularly exposed to arsenic through drinking water and eating rice grown in soil and water containing high amounts of arsenic. Long-term exposure can lead to the deve...

Iron and cancer: more ore to be mined

The regulation of iron metabolism is altered in tumour cells. Changes in iron regulation enhance iron influx and retention. This leads to altered cellular processes that foster cancer growth and metas...

News From The Journal Of Clinical Investigation: March 25, 2013

A new therapeutic target in iron overload disorders Iron is required for multiple cellular functions, including the synthesis of hemoglobin, but a buildup of excess cellular iron can be toxic. Hepcidi...

Phase-transfer-catalysed asymmetric synthesis of tetrasubstituted allenes

Substituted allenes with axial chirality are of great utility in organic chemistry owing to their unique structure and reactivity, but synthetic methods to access them are limited. Here, a catalytic a...

Iron Supplements May Cut Fatigue in Some Premenopausal Women

Even women with iron stores that fall within the normal range appear to benefit from iron supplements; experts suggest the cutoff for iron-deficient anemia may need to be lowered. Medscape Medical N...

Al13Fe4 as a low-cost alternative for palladium in heterogeneous hydrogenation

Replacing noble metals in heterogeneous catalysts by low-cost and ubiquitous substitutes such as iron is highly desirable especially because it does not bear potential health risks. A low cost and env...

Rhodium(III)-Catalyzed Intermolecular Direct Amination of Aromatic C-H Bonds with N-Chloroamines.

A Rh(III)-catalyzed direct aromatic C-H amination is achieved using N-chloroamines as a reagent. Furthermore, we also developed a one-pot amination protocol involving in situ chlorination of the secon...

A direct intramolecular C-H amination reaction cocatalyzed by copper(II) and iron(III) as part of an efficient route for the synthesis of pyrido1,2-abenzimidazoles from N-aryl-2-aminopyridines.

A novel and efficient synthesis of pyrido[1,2-a]benzimidazoles through direct intramolecular aromatic C-H amination of N-aryl-2-aminopyridines has been developed. The reaction, cocatalyzed by Cu(OAc)(...

Rhodium-catalyzed regioselective amination of secondary allylic trichloroacetimidates with unactivated aromatic amines.

The use of unactivated aromatic amines in the rhodium-catalyzed regioselective amination of secondary allylic trichloroacetimidates is explored. The desired N-arylamines are obtained in high yields an...

Catalytic ch amination with aromatic amines.

Aniline joins the club: A β-diketiminato copper(I) catalyst enables CH amination of anilines employing low catalyst loadings to preclude oxidation to the diazene ArNNAr. Electron-poor anilines...

Highly efficient transformation of levulinic acid into pyrrolidinones by iridium catalysed transfer hydrogenation.

Levulinic acid (LA) is transformed into pyrrolidinones via iridium-catalysed reductive amination using formic acid as the hydrogen source under aqueous conditions. The catalytic system is the most act...