Thrombin W-L

Thrombin GenTrac

Thrombin Omrix

Thrombin rDNA

Thrombin-Collagen

Postoperative Hypotonic vs Isotonic Solutions in Kids

This F1000 commentary reports on a study whose findings support the use of isotonic solution postoperatively in children. Faculty of 1000

Self‐assembled DNA‐based giant thrombin nanoparticles for controlled release

Protein‐aptamer interactions have been used in a wide range of fields including medical diagnosis and protein delivery. Herein, we report a method for thrombin delivery with thrombin binding aptamer...

Isotonic Fluids Helpful in Diabetic Ketoacidosis in Kids

Children with diabetic ketoacidosis (DKA) treated with isotonic fluids in the so-called Dallas protocol may fare better than those managed according to 2006 American Diabetes Association recommendatio...

Thrombin sponge speeds cervical spine surgery discharge

Application of a thrombin-soaked sponge after posterior cervical spine surgery allows patients to leave hospital earlier than normally expected, suggests research.

The Medicines Company in over $105 million deal with Bristol-Myers for Recothrom; buys Incline Thera

Pharma major Bristol-Myers Squibb (NYSE: BMY) and fellow-USA-based The Medicines Company (Nasdaq: MDCO) have signed a global license and two year collaboration for Recothrom (thrombin alfa), a recombi...

[Comment] Improving long-term outcome after myocardial infarction

Despite several large clinical trials, the best treatment strategy for long-term secondary prevention of thrombosis after myocardial infarction is unclear. Increasing anti-thrombotic treatment, especi...

DKA Improves with Isotonic Fluid Protocol (CME/CE)

WASHINGTON (MedPage Today) -- Rates of death and disability were much lower among children with diabetic ketoacidosis (DKA) when they were treated with a consistent protocol that supplied high leve...

A novel hemostatic sealant composed of gelatin, transglutaminase and thrombin effectively controls liver trauma-induced bleeding in dogs

A Series of Natural Flavonoids as Thrombin Inhibitors: Structure-activity relationships.

A series of natural flavonoids has been evaluated as potential inhibitors of thrombin using the optimized method of thrombin time. Myricetin and quercetin have shown to be the best thrombin inhibitors...

By increasing the affinity of heparin for fibrin, zn(2+) promotes the formation of a ternary heparin-thrombin-fibrin complex that protects thrombin from inhibition by antithrombin.

Heparin binds fibrin and, by bridging thrombin onto fibrin, promotes the formation of a ternary heparin-thrombin-fibrin complex that protects thrombin from inhibition by antithrombin. Because thrombin...

Thrombin generation in Cushing's Syndrome: do the conventional clotting indices tell the whole truth?

Cushing's Syndrome (CS) is associated with an increased mortality, where hypercoagulability seems to have a crucial role in both arterial and venous thrombosis. Parameters of in vitro thrombin generat...

Thrombin-induced autophagy: A potential role in intracerebral hemorrhage.

Autophagy occurs in the brain after intracerebral hemorrhage (ICH) and thrombin contributes to ICH-induced brain injury and cell death. In this study, we investigated whether thrombin may activate aut...

Direct thrombin inhibitors in cardiovascular disease.

Limitations of commonly used anticoagulants, unfractionated heparin, low-molecular-weight heparin, and oral vitamin K antagonists have prompted the development of alternative therapies. Direct thrombi...