Search Results for "Itraconazole Therapuetic Drug Monitoring"
Original Source: Level of Evidence for Therapeutic Drug Monitoring of Itraconazole.
Itraconazole is a triazole antifungal agent that is active against Aspergillus, histoplasmosis, and rare fungal infections. Itraconazole exhibit marked variability in drug concentration as a result of inconsistent absorption, metabolism, or interaction with concomitant medications. Preclinical and clinical data have exhibited a relationship between serum concentrations and treatment efficacy or toxicity, thus therapeutic drug monitoring (TDM) of itraconazole is largely used to optimise therapy. The analysis...
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Mylan wins final FDA approval for Itraconazole capsules ANDA
Mylan Pharmaceuticals has won final FDA approval for its abbreviated new drug application (ANDA) of Itraconazole capsules, 100mg, the generic version of Janssen Pharmaceutical's Sporanox capsules.
Type: Original PaperCocrystals of itraconazole, an antifungal drug with poor bioavailability, and succinic acid, a water-soluble dicarboxylic acid, were formed by gas antisolvent (GAS) cocrystallizati...
Mylan receives FDA approval for generic Sporanox ANDA
Mylan Inc. today announced that its subsidiary Mylan Pharmaceuticals Inc. has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) f...
Mylan Launches Generic Version of Sporanox® Capsules
PITTSBURGH, July 27, 2012 /PRNewswire/ -- Mylan Inc. (Nasdaq: MYL) today announced that its subsidiary Mylan Pharmaceuticals Inc. has received final approval from the U.S. Food and Drug Admin...
Type: Brief CommunicationFor poorly soluble weak bases, the possibility of drug precipitation upon entry into the small intestine may affect the amount of drug available for uptake through the intesti...
AAPS PharmSciTech: Ditosylate Salt of Itraconazole and Dissolution Enhancement Using Cyclodextrins
Type: Original PaperSalt formation has been a promising approach for improving the solubility of poorly soluble acidic and basic drugs. The aim of the present study was to prepare the salt form of itr...
Type: Original PaperNanoparticles, of the poorly water-soluble drug, itraconazole (ITZ), were produced by the Advanced Evaporative Precipitation into Aqueous Solution process (Advanced EPAS). This pro...
MOH To Increase Monitoring Against Hospital Bribes
China’s Ministry of Health said it will further combat bribery of doctors and hospital staff by increasing monitoring, taking a hard line in concentrated drug procurements and delinking hospitals an...
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Level of Evidence for Therapeutic Drug Monitoring of Itraconazole.
Itraconazole is a triazole antifungal agent that is active against Aspergillus, histoplasmosis, and rare fungal infections. Itraconazole exhibit marked variability in drug concentration as a result of...
Introduction: Fungal infections are a major source of global morbidity and mortality. Itraconazole is a triazole antifungal agent that is widely used for the prevention and treatment of fungal infecti...
Pharmacokinetic interactions between ciprofloxacin and itraconazole in healthy male volunteers.
Objective. To investigate the pharmacokinetic interaction between ciprofloxacin and itraconazole in healthy male volunteers. Methods. Ten healthy male volunteers were assigned into a 2-sequence, 3-per...
To develop a novel itraconazole-loaded solid dispersion without crystalline change with improved bioavailability, various itraconazole-loaded solid dispersions were prepared with water, polyvinylpyrro...
Phase behavior of itraconazole-phenol mixtures and its pharmaceutical applications.
The aims of this study were to examine the phase behavior of itraconazole-phenol mixtures and assess the feasibility of topical formulations of itraconazole using eutectic mixture systems. Itraconazol...
